Research, Society and Development
August 22, 2021
Myla Christie Araújo Custódio Bonifácio, Pietra Bruna Batrbosa Bento, Kaynara Trevisan et al.
1 citation
Este trabalho discute acerca da ação da psilocibina no organismo humano e seu potencial terapêutico enquanto tratamento principal ou adjuvante para certos distúrbios psiquiátricos, mais especificamente a depressão e a ansiedade, como aquelas encontradas em pacientes que estão em cuidados paliativos e enfrentando o processo de fim de vida, mas também em pacientes nos quais o tratamento...
Frontiers in Psychology
August 19, 2021
Jessica Sophie Corneille, David Luke
61 citations
Spontaneous Spiritual Awakenings (SSAs) are subjective experiences characterised by a sudden sense of direct contact, union, or complete nondual merging (experience of oneness) with a perceived ultimate reality, the universe, “God,” or the divine. These profound transformative experiences have scarcely been researched, despite extensive anecdotal evidence suggesting their potential to catalyse...
Pharmacopsychiatry
August 4, 2021
Sandeep M. Nayak, Natalie Gukasyan, Frederick S. Barrett et al.
67 citations
Abstract Introduction Psychedelics show promise in treating unipolar depression, though patients with bipolar disorder have been excluded from recent psychedelic trials. There is limited information on the use of classic psychedelics (e. g., LSD or psilocybin) in individuals using mood stabilizers to treat bipolar disorder. This is important to know, as individuals with bipolar depression may...
Oxford University Press eBooks
August 1, 2021
Chris Letheby
Philosophy of Psychedelics is the first scholarly monograph in English devoted to the philosophical analysis of psychedelic drugs. Its central focus is the apparent conflict between the growing use of psychedelics in psychiatry and the philosophical worldview of naturalism, which holds that the natural world is all that exists. The book reviews scientific evidence that psychedelics such as...
Cells
July 27, 2021
Dasiel O Borroto-Escuela, Patrizia Ambrogini, Manuel Narváez et al.
29 citations
The heteroreceptor complexes present a novel biological principle for signal integration. These complexes and their allosteric receptor–receptor interactions are bidirectional and novel targets for treatment of CNS diseases including mental diseases. The existence of D2R-5-HT2AR heterocomplexes can help explain the anti-schizophrenic effects of atypical antipsychotic drugs not only based on...
July 26, 2021
Cindy Brooks Dollar
8 citations
Psychedelic research is said to be going through a renaissance with widespread public and political attention on psychedelics' ability to clinically resolve various medicalized issues.The prevailing cultural narrative of psychedelics almost touts it as a panacea when used in regulated, clinical settings under the supervision of a trained guide.While clinical studies are certainly informative,...
F1000Research
July 22, 2021
Vivian Siegel, Benjamin Emmert-Aronson
5 citations
Background: Practitioners in a variety of spiritual/religious traditions have described “mystical experiences”, defined by a common set of qualities. The “Mystical Experience Questionnaire” (MEQ30) provides a validated and quantitative measure of mystical experience, and has been used successfully to demonstrate that the hallucinogenic substance psilocybin triggers a mystical-type experience....
July 15, 2021
Julia M. Salamat, Kodye L. Abbott, Patrick Flannery et al.
Illicit substances refer to the compounds that are either stimulatory or inhibitory to the central nervous system. These compounds cause hallucinogenic effects, hence, their use has been forbidden. This chapter emphasises the psychoactive illicit substances of fungal origin. Psilocybin is present in hallucinogenic mushrooms which are also called 'magic mushrooms'. It discusses the neurological...
PsyArXiv
July 8, 2021
Chris Letheby
preprint
In this précis I summarise the main ideas of my book Philosophy of Psychedelics . The book discusses philosophical issues arising from the therapeutic use of classic psychedelic drugs such as psilocybin and LSD. The book is organised around what I call the Comforting Delusion Objection to psychedelic therapy: the concern that this novel and promising treatment relies essentially on the...
Expert Review of Clinical Pharmacology
July 6, 2021
E. Schenberg
Dear Editors, Unblinding is an important confounding in pharmacological research potentially affecting rigor and objectivity of the scientific data underlying evidence-based medicine. Therefore, I want to commend the work by Muthukumaraswamy et al. [1] reporting on this problem in clinical trials with psychedelics (Ketamine, LSD, psilocybin and ayahuasca), which are rapidly becoming a focus of...