With its catchy title, historian Benjamin Breen's Tripping on Utopia brings together controversial findings about the human mind, social engineering, and professional responsibility.He delineates the time frame and focus of an inquiry into psychoactive drug research by stating that "Timothy Leary and the Baby Boomers did not usher in the first psychedelic era.They ended it" (3).The Controlled...
Focusing on two ‘expanded’ films - Bruce Conner’s Looking for Mushrooms (1959-65) and Stan Brakhage’s Eye Myth (1967) - this paper stages an encounter between psychedelic ‘expanded’ cinema, the writings of Alan Watts, and the field of posthuman philosophy. Drawing special attention to the materiality of film and its relation to the experience of altered states of consciousness, this paper will...
Abstract Background Psychedelic use and its impact on well-being is garnering a lot of research attention, however, little has been done to understand the potential associations between multiple characteristics of the psychedelic experience and psychological flexibility (PF), which encompasses a conscious awareness of thoughts and behavior, allowing individuals to adapt to new experiences and...
Abstract Objective Recent years have witnessed a resurgence in research exploring the therapeutic potential of classic psychedelics like psilocybin and LSD for treating mental disorders. However, there is a limited knowledge regarding the epidemiology of classic psychedelics consumption and the factors associated with their recreational use in Poland. Methods A representative sample of Polish...
Psychedelics known for mankind from millennia are class of compounds that alter consciousness, affect perception and produce hallucinations. Classic psychedelics such as psilocybin, mescaline, dimethyltryptamine (DMT) and lysergic acid diethylamide (LSD) have pharmacodynamic serotonergic effects. They are known to exert profound effects on neuroplasticity i.e. alteration of neuronal structure...
Este estudio exploró las experiencias subjetivas asociadas al consumo doméstico y autónomo de hongos psilocibios en un usuario primerizo con énfasis en los procesos de autopercepción y adaptación cotidiana. Se empleó un enfoque cualitativo mediante un estudio de caso único, con análisis temático inductivo aplicado a entrevistas semiestructuradas realizadas antes y después de la experiencia, así...
Abstract Intracellular calcium (Ca 2+ ) is ubiquitous to cell signaling across biology. While existing fluorescent sensors and reporters can detect activated cells with elevated Ca 2+ levels, these approaches require implants to deliver light to deep tissue, precluding their noninvasive use in freely behaving animals. Here we engineered an enzyme-catalyzed approach that rapidly and...
Psychedelics like LSD (Lysergic acid diethylamide) and psilocybin are known to modulate perceptual modalities due to the activation of mostly serotonin receptors in specific cortical (e.g., visual cortex) and subcortical (e.g., thalamus) regions of the brain. In the visual domain, these psychedelic modulations often result in peculiar disturbances of viewed objects and light and sometimes even...
Despite advancements in policies governing psychedelic substances globally, our understanding of real-world psychedelic use and its variations across international jurisdictions remains limited. We implemented the Global Psychedelic Survey (GPS) to capture information about psychedelic consumer characteristics, access, and usage patterns around the world. The GPS was administered online in...
In recent years, scientists have initiated a renaissance in psychedelic research following decades of prohibition. Compounds such as ketamine, LSD, and psilocybin 'once primarily associated with recreational use' are now being investigated for their therapeutic potential, with promising results. An estimated 40-60% of people with post-traumatic stress disorder (PTSD) do not respond to selective...