Nature Communications
August 3, 2026
Frederik Gudmundsen, Julia Czurylo, Daniel Ryskamp Rijsketic et al.
Serotonergic psychedelics show therapeutic potential across neuropsychiatric disorders despite transient acute effects. These compounds share serotonin 2 A receptor agonism but differ in broader pharmacology, motivating a systematic comparison of their neurobiological effects. Here, we use [18 F]FDG-PET in rats to assess acute and one-week effects of psilocybin, LSD, and 2C-B on brain metabolic...
Papyrus : Institutional Repository (Université de Montréal)
August 1, 2026
Morgan Vallée
L'expérience psychédélique désigne le type particulier d'expérience de conscience que l'on peut vivre à la suite de la prise de substances telles que le LSD ou la psilocybine. Si l'expérience psychédélique a surtout été étudiée en pharmacologie et en neurosciences, plusieurs études récentes en anthropologie et en sociologie se sont intéressées à la conceptualisation de celle-ci en tant...
Suchttherapie
August 1, 2026
Yann David Kippe, Christopher Poppe, Dimitris Repantis et al.
Zusammenfassung Klassische Halluzinogene („Psychedelika“) wie Lysergsäurediethylamid (LSD), Psilocybin, N,N-Dimethyltryptamin (DMT) und 5-Methoxydimethyltryptamin (5-MeO-DMT) werden zurzeit wieder als potenzielle Behandlungsoptionen bei Substanzgebrauchsstörungen untersucht. Psychedelika entfalten ihre Wirkung über eine Aktivierung von serotonergen 5HT-2a Rezeptoren im zentralen Nervensystem,...
ACS Chemical Neuroscience
August 1, 2026
Role of β-Arrestin2 Signaling in Neuropharmacological Effects of Psychedelic Drugs.
Current Bioactive Compounds
August 1, 2026
Priya Chaudhary, Pracheta Janmeda
Background: Mushrooms, usually used for their nutritional and culinary properties, have recently gained attention for their medicinal effects, so that they are not only used as dietary foods but also as mycotherapeutics, nutraceuticals, and food supplements. Objective: The aim of this study is therefore to educate readers about various mushrooms with medicinal benefits. Methodology: A large...
International Journal of Drug Policy
August 1, 2026
Myfanwy Graham, Yimin Ge, Rosalie Liccardo Pacula et al.
1 citation
We know little about the extent psychedelic substances are consumed therapeutically and/or discussed with medical professionals despite renewed global interest in these substances. We examined self-reported responses from the 2023 International Cannabis Policy Study (ICPS) in repeated cross-sectional surveys in Canada, the United States, Australia, and New Zealand. The survey included questions...
International Journal For Multidisciplinary Research
July 31, 2026
Eric P. Rubenstein
Set, setting, preparation, and integration are widely recognized as important dimensions of psychedelic experiences. However, these concepts often remain too general to specify how preparation, containment, and aftercare should differ across substances, routes of administration, acute duration, residual effects, bodily condition, and interaction exposure. This article proposes the...
npj Mental Health Research
July 30, 2026
Lorraine Li, Paige Seath, Nadav Liam Modlin et al.
Abstract Research examining psychological outcomes following psychedelic use has grown substantially, yet the role of childhood trauma in shaping these responses remains insufficiently understood. This scoping review mapped the literature examining childhood trauma in relation to post-psychedelic psychological outcomes. Thirty-four sources met inclusion criteria and investigated substances...
Medicina contemporânea
July 28, 2026
Larissa Barbosa Lopes, Ana Glaucia Paulino Lima
O interesse científico pelos psicodélicos como alternativa terapêutica para transtornos mentais tem crescido expressivamente nas últimas duas décadas, impulsionado por ensaios clínicos que demonstram resultados promissores em pacientes com depressão resistente ao tratamento, transtorno de estresse pós-traumático, ansiedade relacionada a doenças graves e transtornos por uso de substâncias....
Oxford University Press eBooks
July 22, 2026
Julian Kiverstein
Abstract Psychedelic substances such as psilocybin, LSD, ayahuasca, DMT, or mescaline, when employed with knowledge and skill, can sometimes lead to profoundly meaningful and transformative subjective experiences. This chapter discusses how the predictive processing theory can further our understanding of these deeply meaningful spiritual psychedelic experience. It makes a more specific...