The crystal structure of Psilocin, the minor hallucinogenic component of Teonanácatl, the sacred mushroom of Mexico, has been determined. Crystals are monoclinic, space group P21/c, a= 1060(3), b= 853(2), c= 1251(3) pm, β= 91·25(30)°. Data were collected on a linear diffractometer employing graphite monochromatised Mo-Kα radiation. The structure was solved by direct methods and refined by block...
The crystal structure of psilocybin, the major hallucinogenic component of Teonanácatl, the sacred mushroom of Mexico, has been determined in crystals of the monomethanolate. Crystals are monoclinic, space group P21/c, a= 1264(1), b= 2911(2), c= 884·7(6) pm, β= 107·37(2)°, and contain two molecules of psilocybin and two molecules of methanol of solvation per asymmetric unit. Data were collected...
There is a “natural” tendency to misjudge the position of the visual as compared to the gravitational vertical. A 160 µg/kg psilocybin-induced accentuation of this misjudgment in 16 college-age volunteers, and a further augmentation in their accentuated drug response after exposure to strong body distortion is reported.
Abstract Nach klassischen Methoden wird aus dem Phenol (I) über die Stufen (II), (III), (IV) und (V) bzw. (VII) und (VIII) das Amin (VI) (60 bzw. 90% Ausbeute) gewonnen, dessen Diazoniumsalz mit CuSO 4 zu dem Phenol (IX) zersetzt wird.
Using apparent fronto-parallel plane (AFP) monitoring techniques, the relative stability of the abathic plane, i.e., Euclidean visual space, was investigated in 16 volunteers with a median age of 23.5 years under 160 µg/kg psilocybin-induced ergotropic arousal. Handwriting area and pressure were also measured in the same subjects.
The psychotomimetic agents psilocybinl~2 (1)O\p/ OH and its dephosphorylated derivative psilooin273 were 0, ' '0-first isolated214 from the hallucinogenic Mexican + mushroom Psilocybe mexicanu Heim.The presence C H C H H e 2 of psilocybin, sometimes accompanied by psilooin, \ has subsequently been demonstrated in a number of 2 (1)species of the genus Psilocybe from Mexico,2J*6 North America,7-9...
The influence of personality structure on the stability of perceptual performance, specifically the degree of reproducibility under hypnotic induction of the psilocybinproduced lowering of spatial distortion thresholds, was investigated in two "variable" and two "stable" psilocybin reactors, that is, subjects who displayed variable and stable MMPI profiles under both control conditions and the...
Autonomic, perceptual, and behavioral changes induced by 160 µg/kg psilocybin were studied in a homogenous sample of 15 self-selected College educated male and female volunteers. The subjects were rank ordered as to the extent of drug-induced psychopathology using their Minnesota Multiphasic Personality Inventory pre-drug to drug peak differences scores. Extent of variability on simple...
ScienceJanuary 13, 1967L. P. Gilmour, R. D. O’brien7 citations
Psilocybin, a hallucinogen, formed a blue color with a subfraction of rat-brain mitochondria believed to contain nerve-ending particles. Color formation increased with p H, did not require oxygen, and involved a component that could not be solubilized. The effect was not shown by chemically related neuroactive compounds, such as bufotenine and serotonin, and was antagonized by only tyramine or...