Objectives: Prolonged disorders of consciousness (DoC) present complex diagnostic and therapeutic challenges. This study aimed to evaluate the accuracy of two ChatGPT models (ChatGPT 4o and ChatGPT o1) in answering questions about prolonged DoC, framed as if they were posed by a patient's relative. Secondary objectives included comparing performance across languages (English vs. Italian) and...
Objective. Resting electroencephalographic activity is typically indistinguishable from a filtered linear random process across a diverse range of behavioural and pharmacological states, suggesting that the power spectral density of the resting electroencephalogram (EEG) can be modelled as the superposition of multiple, stochastically driven and independent, alpha band (8-13 Hz) relaxation...
N, N-Dimethyltryptamine (DMT), a potent serotonergic psychedelic, bridges ancient wisdom and modern science. The mechanisms underlying its powerful psychedelic effects and out-of-body experiences continue to intrigue scientists. The functional role of DMT remains ambiguous. This paper explores the endogenous presence of DMT in the human body and its diverse neuroregulatory functions, which...
The Physical and Psychological Effects of MeditationPari Patel Meditation has many physical and psychological effects on the human body.Meditation originated from ancient Eastern culture and has been practiced for centuries.Meditation back then was considered a religious practice; however, it is not necessary to be religious to meditate.Trials conducted and respected research show that...
This article proposes visionary realism as a philosophical framework to underlabor for the development of a unified science of spiritual experience. By integrating elements of Roy Bhaskar’s critical realism, Ken Wilber’s integral theory, William James’s radical empiricism, Johann Wolfgang von Goethe’s participatory epistemology, and Rudolf Steiner’s subtle empiricism, visionary realism outlines...
Peak and mystical experiences can be seen as states of consciousness that exist on a spectrum of varying intensity and duration. They are often described as moments of profound joy, ecstasy, and awe that involve feelings of noetic quality, decreased self-salience, and heightened interconnectedness. The renewed interest in psychedelics as a potential tool for therapeutic intervention has been...
This paper introduces Reflective Empiricism, an extension of empirical science that incorporates subjective perception and consciousness processes as equally valid sources of knowledge. It views reality as an interplay of subjective experience and objective laws, comprehensible only through systematic introspection, bias reflection, and premise-based logical-explorative modeling. This approach...
Metacognitive awareness is the ability to reflect upon one's own thinking, experience, and environment. Self-awareness, or the ability to recognize oneself as an individuated self and introspect upon one's own feelings, ideas, and behavior, is a master dimension of consciousness. The argument in this research addresses theories of consciousness, brain origins, and the emergence of...
Understanding the neural processes underlying conscious perception remains a central goal in neuroscience. Visual illusions, whether static or dynamic, provide an effective ecological paradigm for studying conscious perception, as they induce subjective experiences from constant visual inputs. While previous neuroimaging studies have dissociated perceptual interpretation of visual motion from...
This study investigates the interaction of posthumanities and artificial intelligences, with a special focus on how AI developments are reshaping conservation, morals, and humans. As AI systems get more powerful over time, they bring together many assumptions about human uniqueness, cognitive abilities, and moral status. AI keeps opens ways for rethinking human capacity and identity, raising a...