Psicumex
June 1, 2024
Andrea Herrera Solís, Jacqueline Cortés Morelos, Alejandra E. Ruiz Contreras et al.
Los enteógenos han surgido en la investigación clínica como un tratamiento alternativo para la Depresión Resistente al Tratamiento (DRT). Tienen efectos antidepresivos rápidos y duraderos, son ansiolíticos, y mitigan la ideación suicida. Además, inducen emociones positivas y provocan experiencias místicas o espirituales, atributos que pueden contribuir a su eficacia terapéutica, dada la...
Neuroimage
June 1, 2024
Pradeep Kumar, Rajanikant Panda, Kanishka Sharma et al.
20 citations
High-order interactions are required across brain regions to accomplish specific cognitive functions. These functional interdependencies are reflected by synergistic information that can be obtained by combining the information from all the sources considered and redundant information (i.e., common information provided by all the sources). However, electroencephalogram (EEG) functional...
Journal of Psychopharmacology
June 1, 2024
Emily M Gent, Joshua W. Bryan, Maisy A Cleary et al.
20 citations
Alcohol use disorder (AUD) is a major public health issue, posing harmful consequences for individuals and society. Recent advances in addiction research have highlighted the therapeutic potential of ketamine-assisted therapy for AUD. However, the exact mechanisms underlying its effectiveness remain unknown. This double-blind, pilot study aimed to investigate esketamine combined with...
Psychedelic Medicine
June 1, 2024
Dale Terasaki
3 citations
Alcohol use disorder (AUD) is widespread and problematic in the United States, and current pharmacotherapy options have relatively modest effects. Therefore, novel interventions such as ketamine therapy have gained interest as potentially efficacious options, known to generate unique psychotherapeutic experiences. The present secondary analysis examines the acute subjective experiences-both...
Neuropsychopharmacology
June 1, 2024
Conor H. Murray, Joel Frohlich, Connor J Haggarty et al.
30 citations
Neural complexity correlates with one's level of consciousness. During coma, anesthesia, and sleep, complexity is reduced. During altered states, including after lysergic acid diethylamide (LSD), complexity is increased. In the present analysis, we examined whether low doses of LSD (13 and 26 µg) were sufficient to increase neural complexity in the absence of altered states of consciousness. In...
Journal of Cannabis Research
May 31, 2024
S Zhao, Bruna Brands, Pamela Kaduri et al.
13 citations
Cannabis has been shown to impact driving due to changes produced by delta-9-tetrahydrocannabinol (THC), the psychoactive component of cannabis. Current legal thresholds for blood THC while driving are based predominantly on evidence utilizing smoked cannabis. It is known that levels of THC in blood are lower after eating cannabis as compared to smoking yet the impact of edibles on driving and...
Journal of Psychedelic Studies
May 27, 2024
Tehseen Noorani, R. Liebert
2 citations
With a surge in critiques levelled against the evidence generated by randomised controlled trials in the study of psychedelic-assisted therapy (PAT), and the legalization of PAT in select jurisdictions such as Australia, and Oregon and Colorado in the United States, we consider what form the real-world evidence of its effects could take. Specifically, we propose to complement individual-level...
Journal of Psychedelic Studies
May 27, 2024
Lisa L. Gezon
7 citations
This qualitative ethnographic study of a psychedelic integration group in the Southeastern United States contributes to an understanding of the role of supportive communities in processing psychedelic experiences. This article proposes the concept of ‘social efficacy’ to capture the importance of social relationships to the efficacy of psychedelics. Social efficacy refers to a source of...
International Review of Psychiatry
May 23, 2024
Rebecca Ehrenkranz, Manish Agrawal, J. Kim Penberthy et al.
5 citations
Prolonged Grief Disorder (PGD) is distinct from yet related to non-pathologic grief, depression, addiction, and Post-Traumatic Stress Disorder (PTSD) with a prevalence of up to 10% in bereaved populations. Hallmarks of PGD include functional impairment a year or more post-bereavement and intense yearning for the deceased. Current treatments for PGD are typically psychological rather than...
The Oxford Handbook of Psychedelic, Religious, Spiritual, and Mystical Experiences
May 22, 2024
Etzel Cardeña
Abstract Transcendent/mystical experiences have been reported within the hypnotic context from its inception as “animal magnetism/mesmerism. Research on spontaneous experiences during hypnosis and minimal suggestion/neutral hypnosis evidence that such experiences are not an artifact of implicit or explicit hypnotic suggestions but may occur spontaneously when some individuals focus on their...