Mental Health Weekly
January 23, 2026
Valerie A. Canady
Microdosing — once a niche practice whispered about in online forums and tech circles — has firmly entered the mainstream. A new RAND survey suggests that millions of U.S. adults are now taking sub‐perceptual amounts of psychedelics such as psilocybin, LSD and MDMA, often with goals that differ sharply from those associated with traditional, full‐dose use.
Soil use and management
2026
Yacouba Ouedraogo, J. Taonda, Idriss Sermé et al.
Fertiliser microdosing (FM) is widely promoted in sub‐Saharan Africa as a means to improve fertiliser use efficiency in cereal crops. However, combining organic amendments with FM could further increase the agronomic efficiency of the latter because of possible synergies between both practices. This study therefore evaluated whether combining FM with organic amendments enhanced fertiliser use...
International Journal of Agronomy
2026
Parwada Cosmas, Masere T. Philip, Gumbo Albert
The small‐scale farmers of semiarid southern Africa are experiencing chronic water and nutrient shortages due to climate change; however, very few initiatives have been put in place to optimize the production of underutilized drought‐tolerant small grains that currently give poor yields of less than 0.8 t ha −1 using conventional planting techniques. The current experiment was undertaken to...
Human Enhancement Drugs Volume Two
2026
Microdosing psychedelics has attracted growing attention from public commentators, scientists, investors and user communities across the globe. Microdosing is the use of small doses of psychedelic substances such as psilocybin mushrooms and LSD. Its proponents speak of microdosing as a use modality that improves various human abilities and life areas, including cognitive function, mood,...
Neuropharmacology
2026
Luisa Prochazkova, Laura C. Carvalho, Natasza Marrouch et al.
While microdosing psychedelics is increasingly popular for enhancing well-being, its effects on health behavior change (HBC) remain poorly understood. This study investigated self-reported health-related behavior changes and putative underlying psychological mechanisms associated with psychedelic microdosing in a naturalistic setting. A retrospective mixed-method survey was conducted with 365...
Neuroscience & Biobehavioral Reviews
2026
Netta Pinhas, Nofar Eidlman, Avigail Barnea et al.
2 citations
Microdosing - the practice of consuming extremely low doses of classical psychedelic substances that do not elicit overt psychedelic effects - has gained significant attention as a potential method for enhancing cognitive performance. However, findings from controlled studies remain mixed and inconclusive. This preregistered meta-analysis examined the cognitive effects of classical psychedelic...
Palliative & Supportive Care
2026
Fiona Cottam, Alesha Wells, Cerys Clayden et al.
Participation in trials investigating psychedelic-assisted MCP may offer hope for patients and their caregivers. Given the bidirectional relationship in wellbeing between cancer dyads, caregivers should be included alongside patients in such trials.
International Journal of Biosciences
December 23, 2025
Pierre G. Tovihoudji*, Kamarou-Dine Seydou
Soybean cultivation has expanded among farmers in Benin, yet yields remain below potential, mainly due to declining soil fertility and poor seed quality. This study evaluated the effects of organo-mineral microdose fertilization and rhizobium inoculation on the agronomic performance of three soybean varieties in the sub-humid zone of Northern Benin over two consecutive growing seasons. A...
Neuropharmacology
December 1, 2025
Carina Joy Donegan, Dimitri Daldegan-Bueno, Tehseen Noorani et al.
4 citations
Expectations can impact antidepressant treatment and psychedelic therapy, often enhancing placebo effects and influencing outcomes. However, research in this context is lacking. Our study explored the expectations of participants with major depressive disorder (MDD) before microdosing lysergic acid diethylamide (LSD) in an open-label trial. Twenty-three individuals with MDD completed a...
Journal of Advances in Medicine and Pharmaceutical Sciences
November 27, 2025
Roland Mario, Festin Bermudez, Mary Fresthel et al.
Post-detoxification phases of methamphetamine dependence are often characterized by neurophysiological instability, including tremors, insomnia, and anxiety, due to suppressed GABAergic activity and hyperdopaminergic rebound. Traditional Filipino distilled spirit, álak or lambanog, contains trace levels of ethanol and minor fusel alcohols which may exert mild GABA-A receptor agonism when...