AACN advanced critical care
2019
Ruff Joseph Macale Cajanding
3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) has become a popular recreational drug of abuse among young adults, partly because of the belief that it is relatively safe compared with other drugs with the same stimulant and hallucinogenic effects. However, MDMA use has been associated with a wide spectrum of organ toxicities, with the liver being severely affected by its deleterious...
Visual Anthropology
2019
M. Schäuble
1 citation
States of trance and spirit possession have inspired the modernist imagination perhaps more than anything else, as they typically exceed the limits of visual representation. This article investigates different approaches to coping with these challenges, focusing on the works of a group of Italian documentary filmmakers, including Luigi di Gianni, Cecilia Mangini, and Gianfranco Mingozzi, who...
Journal of Psychoactive Drugs
2019
Anne C Wagner, Michael C Mithoefer, Ann T Mithoefer et al.
92 citations
Treatments for posttraumatic stress disorder (PTSD) have evolved significantly in the past 35 years. From what was historically viewed as a pervasive, intractable condition have emerged multiple evidence-based intervention options. These treatments, predominantly cognitive behavioral in orientation, provide significant symptom improvement in 50-60% of recipients. The treatment of PTSD with...
ACS Chemical Neuroscience
December 27, 2018
Patrick Vizeli, Henriette E. Meyer zu Schwabedissen, Matthias E. Liechti
13 citations
Methylenedioxymethamphetamine (MDMA; ecstasy) is used recreationally and has been investigated as an adjunct to psychotherapy. Most acute effects of MDMA can be attributed to activation of the serotonin (5-hydroxytryptamine [5-HT]) system. Genetic variants, such as single-nucleotide polymorphisms (SNPs) and polymorphic regions in 5-HT system genes, may contribute to interindividual differences...
December 7, 2018
Mercedes Guaia Memita Guaia
El MDMA es un potente empatógeno que actúa liberando 5-HT Fue redescubierto en la década de 1970 como un fármaco útil para reducir la ira y la hostilidad en la terapia de pareja Posteriormente comenzó a utilizarse en el ambiente de las fiestas “rave” y su nombre cambió a éxtasis Recientemente, ensayos clínicos han demostrado que posee una eficacia especial en el tratamiento del TEPT resistente...
December 7, 2018
MDMA is a powerful empathogen that works by releasing 5-HT It was rediscovered in the 1970s as a useful drug to break down anger and hostility in couples counseling Later it started to be used in the “rave” scene and its name was changed to ecstasy Recently, trials have shown it to have special efficacy in the treatment of PTSD that has proved resistant to conventional treatments Brain imaging...
December 6, 2018
Todd Lawson
In Tafsir as Mystical Experience, Todd Lawson shows how the Quran may be engaged with for meaning and understanding, the usual goal of mystical exegesis, and also how it may be engaged with through tafsīr in a quest for spiritual or mystical experience. In this earliest of the Báb's extended works, written before his public claim to be the return of the hidden Imam, the act of reading is shown...
Journal of Psychopharmacology
December 1, 2018
Marcela Ot'Alora G, Jim Grigsby, Bruce Poulter et al.
232 citations
Posttraumatic stress disorder often does not resolve after conventional psychotherapies or pharmacotherapies. Pilot studies have reported that 3,4-methylenedioxymethamphetamine (MDMA) combined with psychotherapy reduces posttraumatic stress disorder symptoms. This pilot dose response trial assessed efficacy and safety of MDMA-assisted psychotherapy across multiple therapy teams. Twenty-eight...
Journal of Neuroscience
November 19, 2018
Anthony S. Gabay, Matthew J. Kempton, James Gilleen et al.
40 citations
Social decision-making is fundamental for successful functioning and can be affected in psychiatric illness and by serotoninergic modulation. The Prisoner's Dilemma is the archetypal paradigm to model cooperation and trust. However, the effect of serotonergic enhancement is poorly characterized, and its influence on the effect of variations in opponent behavior unknown. To address this, we...
Neuroscience & Biobehavioral Reviews
November 12, 2018
Felix Müller, Raphael Brändle, Matthias E. Liechti et al.
52 citations
In this meta-analysis, we aimed to assess the evidence from neuroimaging studies for chronic alterations in the brains of MDMA users. The databases PubMed, Embase, and Web of Science were searched for studies published from inception to August 24, 2018, without any language restriction. Sixteen independent studies comprising 356 MDMA users and 311 controls were included. Of these, five studies...