Objetivo: recopilar y analizar la información sobre los efectos de la MDMA obtenida en estudios controlados en humanos. Método: la mayoría de ensayos analizados han sido de diseño enmascarado a doble ciego, cruzados, con asignación aleatoria a la secuencia de tratamientos, y controlados con placebo y/o fármaco patrón. Resultados: además del incremento de la presión y frecuencia cardíaca, la...
Research of hallucinogen abuse rarely extends beyond epidemiology and observed pathology. Even less research has been completed on the special circumstances surrounding the religious use of hallucinogens or on potential therapeutic applications. Rather than offer another basic review on the well-known hazards of illicit hallucinogen use, this paper provides an overview and practice...
Shamans of the Piaroa ethnic group (southern Venezuela) conceive of power in terms of knowledge derived from visionary experiences. Märipa is an epistemology concerning the translation of knowledge derived from the integrative mode of consciousness, induced primarily through the consumption of plant hallucinogens, to practical effect during waking life. I integrate mythological,...
We have recently shown that methylenedioxymethamphetamine (MDMA), methylenedioxyamphetamine (MDA), cathinone and methylenedioxyethylamphetamine (MDEA) have a cocaine-like action to potentiate the contractile actions of noradrenaline but not isoprenaline in the 1-Hz paced rat right ventricle. The purpose of this study was to directly test the actions of these compounds at the noradrenaline...
This study employed the theory of planned behavior (TPB) to investigate the factors underlying intentions to use and use of LSD, amphetamine, cannabis, and ecstasy over 6 months in a sample of students ( N = 461). The TPB provided good predictions of both intentions (mean R 2 = .49) and behavior (mean R 2 = .45). Descriptive norms explained additional variance in intentions for all the drugs,...
MDMA ("Ecstasy") and its analogues such as MDE and MDA are amphetamine derivatives reported to produce an altered state with emotional overtones. Since more than ten years, ecstasy is after cannabis the most frequently used recreational drug by young adults, particularly in the so-called techno-scene. However, according to a recent survey there is an increasing trend for a revival of classic...
The article explores the relationship between mysticism and creativity from a psychoanalytic perspective. First, it first surveys prominent psychoanalytic perspectives on mysticism and creativity, situating British psychoanalyst Marion Milner among them. Milner suggests that the same psychological processes are involved in both creative expression and mystical experiences. A state of paradox,...
Ce travail interroge l’énigme du religieux et de la croyance autour de la rencontre singulière de dix moniales contemplatives, auxquelles ont été proposés un entretien semi-directif approfondi et les tests Rorschach et TAT. Freud a interprété la religion comme étant une illusion pleine d’avenir bien que dénuée de raison – Credo quia absurdum –, gouvernée par le principe de plaisir et...
RationaleAyahuasca, a South American psychotropic plant tea, combines the psychedelic agent and 5-HT(2A/2C) agonist N, N-dimethyltryptamine (DMT) with beta-carboline alkaloids showing monoamine oxidase-inhibiting properties. Current human research with psychedelics and entactogens has explored the possibility that drugs displaying agonist activity at the 5-HT(2A/2C) sites temporally disrupt...
Ecstasy (MDMA), gamma-hydroxybutyrate (GHB), ketamine, and methamphetamine are 4 examples of club drugs that are increasing in popularity. Although the pharmacological classifications of these drugs vary, MDMA has structural similarities to both amphetamine and the hallucinogen mescaline. Ketamine and GHB are anesthetic agents and methamphetamine is a long-acting psychostimulant. Medical visits...