Antoni Rodrı́guez-fornells - The Consciousness Library

Long-term use of psychedelic drugs is associated with differences in brain structure and personality in humans

European Neuropsychopharmacology January 16, 2015 José Carlos Bouso, Fernanda Palhano-Fontes, Antoni Rodrı́guez-fornells et al. 221 citations

Psychedelic agents have a long history of use by humans for their capacity to induce profound modifications in perception, emotion and cognitive processes. Despite increasing knowledge of the neural mechanisms involved in the acute effects of these drugs, the impact of sustained psychedelic use on the human brain remains largely unknown. Molecular pharmacology studies have shown that...

DOI: 10.1016/j.euroneuro.2015.01.008 Default mode network Posterior cingulate Hallucinogen Dissociative +3

Acute effects of ayahuasca on neuropsychological performance: differences in executive function between experienced and occasional users

Psychopharmacology June 20, 2013 José Carlos Bouso, Josep María Fábregas, Rosa María Antonijoan et al. 96 citations

BackgroundAyahuasca, a South American psychotropic plant tea containing the psychedelic 5-HT2A receptor agonist N,N-dimethyltryptamine, has been shown to increase regional cerebral blood flow in prefrontal brain regions after acute administration to humans. Despite interactions at this level, neuropsychological studies have not found cognitive deficits in abstinent long-term...

DOI: 10.1007/s00213-013-3167-9 Ayahuasca Stroop effect Neuropsychology Cognition +1

Effects of ayahuasca on sensory and sensorimotor gating in humans as measured by P50 suppression and prepulse inhibition of the startle reflex, respectively

Psychopharmacology December 1, 2002 Jordi Riba, Antoni Rodrı́guez-fornells, Manel J. Barbanoj 71 citations

RationaleAyahuasca, a South American psychotropic plant tea, combines the psychedelic agent and 5-HT(2A/2C) agonist N, N-dimethyltryptamine (DMT) with beta-carboline alkaloids showing monoamine oxidase-inhibiting properties. Current human research with psychedelics and entactogens has explored the possibility that drugs displaying agonist activity at the 5-HT(2A/2C) sites temporally disrupt...

DOI: 10.1007/s00213-002-1237-5 Ayahuasca Psilocybin Serotonergic Prepulse inhibition +7

Subjective effects and tolerability of the South American psychoactive beverage Ayahuasca in healthy volunteers

Psychopharmacology February 22, 2001 Jordi Riba, Antoni Rodrı́guez-fornells, Gloria Urbano et al. 302 citations

RationaleAyahuasca is a South American psychoactive beverage that contains the naturally occurring psychedelic agent N,N-dimethyltryptamine (DMT). This "tea" has been used for centuries in religious and medicinal contexts in the rain forest areas of South America and is presently gaining the attention of psychedelic users in North America and Europe.ObjectivesIn the present study, the...

DOI: 10.1007/s002130000606 Ayahuasca Psilocybin Anxiety Lysergic acid diethylamide +6

Papers

Long-term use of psychedelic drugs is associated with differences in brain structure and personality in humans

Acute effects of ayahuasca on neuropsychological performance: differences in executive function between experienced and occasional users

Effects of ayahuasca on sensory and sensorimotor gating in humans as measured by P50 suppression and prepulse inhibition of the startle reflex, respectively

Subjective effects and tolerability of the South American psychoactive beverage Ayahuasca in healthy volunteers