Biochemical Pharmacology
September 25, 2018
Amy J. Eshleman, Katherine M. Wolfrum, John F. Reed et al.
&NA; The use of new psychoactive substituted 2,5‐dimethoxy‐N‐benzylphenethylamines is associated with abuse and toxicity in the United States and elsewhere and their pharmacology is not well known. This study compares the mechanisms of action of 2‐(2,5‐dimethoxy‐4‐methylphenyl)‐N‐(2‐methoxybenzyl)ethanamine (25D‐NBOMe), 2‐(4‐ethyl‐2,5‐dimethoxyphenyl)‐N‐(2‐methoxybenzyl)ethanamine (25E‐NBOMe),...
Oxford Scholarship Online
September 20, 2018
Jens Schlieter
The final chapter of the discursive history outlines how Robert Crookall’s and Robert A. Monroe’s books on “astral projection,” but also C. G. Jung and other researchers discussing paranormal and parapsychological phenomena in the 1960s and early 1970s, already assembled almost all phenomena that Moody could bundle in 1975 under the new term “near-death experiences.” However, the chapter points...
Oxford Scholarship Online
September 20, 2018
Jens Schlieter
3 citations
The similarities between the experiences near death and drug experiences have often been stressed. This chapter goes a step further in providing evidence that the consumption of morphine, hashish, and especially more potent hallucinogens such as LSD in the 1960s and 1970s are to be identified as a major component, or “push factor,” of the emerging discourse on near-death. Not only were several...
World Psychiatry
September 7, 2018
Michaela Irwin, D. Piber
tial impact of psychedelic drugs on psychiatry to that of the microscope on biology and, while this analogy may strike some as laughable, let us reflect for a moment that human research with psychedelics has been effectively moribund since the restrictive drug policy reforms of the 1960s-70s, and has only recently been revived. Classic serotonergic psychedelics – such as LSD, psilocybin and...
Frontiers in Psychology
September 4, 2018
Raphaël Millière, Robin Carhart-Harris, Leor Roseman et al.
402 citations
In recent years, the scientific study of meditation and psychedelic drugs has seen remarkable developments. The increased focus on meditation in cognitive neuroscience has led to a cross-cultural classification of standard meditation styles validated by functional and structural neuroanatomical data. Meanwhile, the renaissance of psychedelic research has shed light on the neurophysiology of...
August 21, 2018
Kathryn Emily Dickason
1 citation
In most scholarship, Choreomania conveys a context in which dance is inextricably linked to medicine. Choreomania , or dance mania (from the Greek terms choros , or dance, and mania , or madness), refers to the dance epidemics that swept Europe between the fourteenth and sixteenth centuries. During this time, French, Flemish and German chroniclers reported how hundreds of people erupted in...
ACS Chemical Neuroscience
July 23, 2018
Lindsay P. Cameron, David E. Olson
114 citations
Though relatively obscure, N, N-dimethyltryptamine (DMT) is an important molecule in psychopharmacology as it is the archetype for all indole-containing serotonergic psychedelics. Its structure can be found embedded within those of better-known molecules such as lysergic acid diethylamide (LSD) and psilocybin. Unlike the latter two compounds, DMT is ubiquitous, being produced by a wide variety...
Frontiers in Pharmacology
July 5, 2018
Eduardo Ekman Schenberg
242 citations
Mental disorders are rising while development of novel psychiatric medications is declining. This stall in innovation has also been linked with intense debates on the current diagnostics and explanations for mental disorders, together constituting a paradigmatic crisis. A radical innovation is psychedelic-assisted psychotherapy (PAP): professionally supervised use of ketamine, MDMA, psilocybin,...
International Review of Psychiatry
July 4, 2018
Stephen Ross
103 citations
Cancer is highly prevalent and one of the leading causes of global morbidity and mortality. Psychological and existential suffering is common in cancer patients, associated with poor psychiatric and medical outcomes. Promising early-phase clinical research (1960s to early 1970s) suggested a therapeutic signal for serotoninergic psychedelics (e.g. psilocybin, LSD) in treating cancer-related...
The Sixties
July 3, 2018
Michael Organ
ABSTRACT The Australian artist Martin Sharp (1942–2013) produced a series of psychedelic artworks in London between 1966 and 1968, the most famous of which were the Disraeli Gears record cover for rock group Cream and the Bob Dylan Blowin’ in the Mind poster. Sharp’s work exemplifies the connection between early twentieth century Modernist art movements, Pop art and acid-induced psychedelia of...