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Katherine M. Wolfrum

3 papers in the library · 112 citations · publishing 2014-2023

Papers

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Pharmacologic Activity of Substituted Tryptamines at 5-Hydroxytryptamine (5-HT)2A Receptor (5-HT2AR), 5-HT2CR, 5-HT1AR, and Serotonin Transporter.

Journal of Pharmacology and Experimental Therapeutics January 20, 2023 Laura B. Kozell, Amy J. Eshleman, Tracy L. Swanson et al. 40 citations

Pharmacologic Activity of Substituted Tryptamines at 5-Hydroxytryptamine (5-HT)2A Receptor (5-HT2AR), 5-HT2CR, 5-HT1AR, and Serotonin Transporter.

DOI: 10.1124/jpet.122.001454 (opens in new tab) Full text (opens in new tab) Drug design Medicinal chemistry Therapeutics Neuropharmacology: psychopharmacology +7

Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: high potency agonists at 5-HT2A receptors

Biochemical Pharmacology September 25, 2018 Amy J. Eshleman, Katherine M. Wolfrum, John F. Reed et al.

&NA; The use of new psychoactive substituted 2,5‐dimethoxy‐N‐benzylphenethylamines is associated with abuse and toxicity in the United States and elsewhere and their pharmacology is not well known. This study compares the mechanisms of action of 2‐(2,5‐dimethoxy‐4‐methylphenyl)‐N‐(2‐methoxybenzyl)ethanamine (25D‐NBOMe), 2‐(4‐ethyl‐2,5‐dimethoxyphenyl)‐N‐(2‐methoxybenzyl)ethanamine (25E‐NBOMe),...

Behavioral and neurochemical pharmacology of six psychoactive substituted phenethylamines: mouse locomotion, rat drug discrimination and in vitro receptor and transporter binding and function.

Psychopharmacology March 1, 2014 Amy J. Eshleman, Michael J Forster, Katherine M. Wolfrum et al. 72 citations

Psychoactive-substituted phenethylamines 2,5-dimethoxy-4-chlorophenethylamine (2C-C); 2,5-dimethoxy-4-methylphenethylamine (2C-D); 2,5-dimethoxy-4-ethylphenethylamine (2C-E); 2,5-dimethoxy-4-iodophenethylamine (2C-I); 2,5-dimethoxy-4-ethylthiophenethylamine (2C-T-2); and 2,5-dimethoxy-4-chloroamphetamine (DOC) are used recreationally and may have deleterious side effects. This study compares...

DOI: 10.1007/s00213-013-3303-6 (opens in new tab) Full text (opens in new tab) Phenethylamines Psychoactive compounds Drugs Substances +12