Skip to content

End-of-life distress: all studies

Page 5 of 40: studies 41 to 50 of 391, newest first. Back to the end-of-life distress overview

Research

Psilocybin and Death Anxiety: A Dual-Mechanism Approach to Existential Distress

August 1, 2025 Annabelle Swain

This literature review looks at how psilocybin, the active compound in "magic mushrooms," can help people deal with death anxiety; the deep fear of dying or losing control that shows up in lots of mental health struggles. While traditional treatments like SSRIs and talk therapy work for some people, they don't always get to the root of the problem. Psilocybin works differently. It changes brain...

Palliative care providers' experiences of mindfulness and resilience: An interpretative phenomenological analysis.

Complementary Therapies in Clinical Practice July 21, 2025 Wei-Ting Lai, Li-Yu Yang, Hsun-Kuei Ko et al. 1 citation

Although mindfulness is widely acknowledged to foster resilience, limited research has examined how palliative care providers sustain this practice and how it shapes their resilience. This study explores how providers with sustained mindfulness practice, understand, and embody the cultivation of resilience across personal and professional domains. Fifteen palliative care providers (three...

Exploring psilocybin's role in mental health and palliative medicine: a path to improved well-being.

Expert Opinion on Emerging Drugs June 1, 2025 Maria-Alejandra Umbacia, Marta Ximena Leon, Jose-Manuel Quintero et al.

Although long known for their psychoactive effects, psychedelic drugs have only recently been investigated for medicinal use. Psilocybin has attracted the greatest interest with studies suggesting that it may be a useful agent in psychiatry and in palliative care. Clinical trials that included psilocybin were searched in PubMed, Embase, and ClinicalTrials.gov, demonstrating that adult...

Psilocybin as a Tool in the Management of Palliative Care: An Historical, Pharmacological and Clinical Approach

Medical & Clinical Case Reports Journal May 19, 2025 Andrés David Turizo Smith, Natalia Jaramillo, Diana Milena Berrío Cuartas

Psilocybin, a psychedelic compound in certain mushrooms, has been used for centuries in spiritual ceremonies and neuropsychiatric therapy.Despite its stigmatization as a Schedule I substance in 1970, research into psilocybin has resurged since the early 2000s, particularly in psychiatry and palliative care.This review examines psilocybins potential to improve the quality of life in palliative...

DOI: 10.51219/mccrj/andres-david-turizo-smith/233 (opens in new tab) Psilocybin Palliative care Intensive care medicine Hallucinogen +2

Psychedelics in Palliative Care

May 1, 2025 2 citations

Abstract This is the first book to explore the use of psychedelic medicines in palliative care and addiction medicine. Bringing together a diverse team of palliative physicians, therapists, researchers, spiritual guides, and entrepreneurs, the book explores the history, cultural significance, science, and legal status of eight major psychedelic medications. Each medication holds fascinating...

Evaluation of a Five-Minute Meditation Intervention During Weekly Palliative Care Clinical Rounds.

Journal of Palliative Medicine April 26, 2025 Alyssa A Gonzalez, Gladys Janice Jimenez-Torres, Bryan M Fellman et al.

Introduction: Palliative care professionals experience high levels stress and burnout. Meditation improves stress and well-being, with group interventions more promising than individual-level efforts. This study assessed participation, satisfaction, helpfulness, and integration of a five-minute group meditation during weekly educational rounds. Methods: Seventy clinicians were invited to...

Roadmap for Equitable Access and Responsible Use of Psilocybin-Assisted Psychotherapy in Palliative Care

Palliative Medicine Reports April 17, 2025 Michel Dorval, Sue-Ling Chang, Houman Farzin et al. 3 citations

Psilocybin-assisted psychotherapy represents a promising addition to palliative care interventions, potentially improving quality of life by addressing existential distress. Despite its safety and effectiveness, this therapy remains limited in Canada, underscoring the need for improved access to ease suffering from life-threatening illnesses. However, important questions remain regarding how to...

DOI: 10.1089/pmr.2024.0108 (opens in new tab) Psilocybin Palliative care Psychotherapist Hallucinogen

Therapeutic Potential of Psilocybin-Assisted Therapy in Hospice and Palliative Care

Revista Cacto - Ciência Arte Comunicação em Transdisciplinaridade Online April 3, 2025 Ana Cláudia Mesquita Garcia

Psilocybin-assisted therapy (PAT) has gained recognition as an innovative intervention in hospice and palliative care, demonstrating potential in mitigating the psychological, spiritual, and existential distress experienced by patients with serious illnesses. This article explores the role of PAT within these care settings, emphasizing its influence on various dimensions of human suffering, as...

DOI: 10.31416/cacto.v5i1.1448 (opens in new tab) Psilocybin Palliative care Hospice care Psychotherapist +2

A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care

Journal of Hospice and Palliative Nursing April 1, 2025 Megan Miller, Molly Meyers, Annona Martin et al.

Psychedelic-assisted therapy (PAT) involves supported experiences with psychedelic medicines in carefully curated environments. Early evidence suggests possible utility of PAT for addressing psychosocial-spiritual-existential concerns, yet gaps remain in understanding findings related to PAT's role in palliative care. This rapid review aims to synthesize current literature on applications of...

Palliadelic: A neologism that refers to the use of psychedelics in hospice and palliative care settings

Progress in Palliative Care April 1, 2025 Jaime Andrés Vinasco Barco, Ana Cláudia Mesquita Garcia

This article discusses the neologism ‘palliadelic’ to designate the use of psychedelics in palliative care (PC) settings. Combining the concepts of ‘palliative’ and ‘psychedelic’, the term aims to describe interventions that use psychedelic substances to alleviate the psychological, spiritual, and existential suffering of patients with serious or incurable illnesses, or at the end of life....