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Palliative & Supportive Care August 5, 2026
Mindfulness as the missing link in spiritual care: Reframing palliative care practice through presence.
Journal of Health and Nutrition Research August 1, 2026 Ahmad Syaripudin
Advanced cancer patients in palliative care frequently face severe existential anxiety and diminished quality of life (QoL). While managing this psychological distress is critical, pharmacological interventions often present adverse side effects. This quasi-experimental study aimed to evaluate the effectiveness of a structured Mindfulness-Based Nursing Intervention (MBNI) on anxiety levels and...
Journal of Pain and Symptom Management August 1, 2026 Stefan Aguiar, Mary Makarious, Orly Lipsitz et al.
Depression and existential distress are highly prevalent among patients with advanced cancer, and there is growing evidence for ketamine as a rapidly acting antidepressant in the population, but few studies have examined existential distress outcomes with ketamine treatment. The INKeD-PC trial demonstrated efficacy of intranasal racemic ketamine for depression in patients with cancer receiving...
The American journal of hospice & palliative care July 22, 2026
Effect of a 5-Minute Mindfulness-of-Gratitude Practice on Suffering and Spiritual Well-Being in Palliative Care Inpatients: A Randomized Controlled Study.
Open Science Framework July 17, 2026 Stephen P. Lewis preprint
Objective: The objective of this narrative review is to understand what forms of spirituality screening and spiritual support are available to individuals with serious or life-threating illness involved in psychedelic-assisted therapies. Introduction: In addition to physical pain related to disease and treatment processes, people encountering serious illness frequently experience psychological...
Medycyna Paliatywna July 15, 2026 Maciej Sulerzycki, Katarzyna Pomykała, Katarzyna Giemza et al.
In recent years, there has been a growing interest in the therapeutic use of psychedelics. In palliative medicine, they are being considered as an alternative approach to treating depression, existential distress, and chronic pain conditions. This review presents current literature on the use of psychedelic substances such as psilocybin, lysergic acid diethylamide,...
medRxiv July 14, 2026 Ali J Zarrabi, Tanja Mletzko, George H. Grant et al. preprint
Demoralization, a syndrome of helplessness, hopelessness, and loss of meaning and chronic pain are common sources of distress in early palliative care. Psilocybin-assisted therapy (PAT) is an emerging intervention with preliminary data suggesting improvements in pain and demoralization. To date, PAT has not been studied among people living with both demoralization and chronic pain nor has it...
International Journal of Drug Policy July 6, 2026 Sarah Kratina, Robert Schwartz, Carol Strike et al.
Canada's evolving attitudes toward psychedelic interventions in palliative and end-of-life care reflect a departure from historically prohibitionist policies and an emerging recognition of their therapeutic potential for individuals facing end-of-life distress. This shift parallels international regulatory developments in jurisdictions such as the United States, Australia and parts of Europe,...
BMC Medicine July 6, 2026 Hannah Adler, Rebecca Filipic, Dr Maria Gonzalez et al.
BACKGROUND: Existential distress is commonly experienced by people with cancer, yet there are limited treatment options. The therapeutic potential for psychedelic-assisted therapy (PAT) utilising psilocybin for this cohort is underexplored, with emerging literature showing clinical improvements in wellbeing. In Australia there is limited knowledge on healthcare professionals' (HCPs') attitudes,...
Pain Management Nursing July 1, 2026 Aline Maria de Oliveira Rocha, Cláudio Arnaldo Len, Flávia H. Santos et al.
OBJECTIVE: To evaluate and compare the effectiveness of mind-body therapies for managing symptoms and improving quality of life in children receiving palliative care using a network meta-analysis (NMA). DESIGN: A systematic review and network meta-analysis (PRISMA-NMA guidelines) registered with PROSPERO (CRD42020198399). REVIEW/ANALYSIS METHODS: Comprehensive searches were conducted across...