Classic psychedelics are able to profoundly alter the state of consciousness and lead to acute experiences of ego dissolution – the blurring of the distinction between representations of self and the external world. However, whether repeated use of psychedelics is associated with more prolonged and permanent modifications to the concept of self remains to be investigated. Therefore, we...
Abstract Background and aims This scoping review employed a multifaceted conceptualization of well-being to examine how psilocybin use affects well-being and related sub-concepts in healthy individuals. It investigated which factors influence the relationship between psilocybin use and well-being, what research protocols have been employed, and what underlying mechanisms have been proposed in...
ABSTRACT In this discussion of The Bad Seed: Mystical Experiences and Time Travel in the Treatment of Psychopathy, I focus on the role of psychedelics in the remarkable clinical account Burton offers. A model for understanding psychedelic action in psychoanalytic terms is put forth, and the account of Seth’s journey is framed in this light. The understanding of psychedelics as facilitating a...
ABSTRACT This is a reply to the discussions by Arthur Fox, Megan Rundel, and Jeffrey Guss. Clarification is made on the utility of diagnosis, as well as further elaboration on what is common to both psychedelic states and the altered states of consciousness encountered in deep psychoanalytic work. Additional thoughts on the integration of a relational multiple self-state model with psychedelic...
European PsychiatryOctober 23, 2023O. Martin-Santiago, G. Guerra-Valera, C. Alario-Ruiz et al.
Introduction The presence of perceptual disturbances and psychotic symptoms associated with substance abuse are widely known. While the abuse of substances is becoming more widespread, there is a general perception that their use entails fewer risks. 25I-NBOMe is a recently introduced hallucinogenic drug producing visual hallucinations and euphoria. Although people consume it like LSD, its...
This philosophical investigation is motivated by the common association between happiness and self-transcendence, and a question posed by Freud: “Why is it so hard for men to be happy?” I consider the answers given in three key texts from the psychoanalytic tradition, Daniel Kahneman’s Thinking, Fast and Slow, Sigmund Freud’s Civilization and its Discontents, and Abraham Maslow’s The Farther...
The studies of mysticism have traditionally emphasized a common core centered around experiences of ego dissolution and unity. However, this focus on a central set of experiences tends to downplay the non-central aspects, resulting in a limited understanding that may not encompass many other types of extraordinary experiences. This paper proposes a layered hierarchy model of mysticism, which...
ABSTRACT The scientific study of psychedelic, religious, spiritual, and mystical (PRSM) experiences can be advanced by applying culturally inclusive qualitative methodologies that illuminate the breadth and depth of individual experiences in a variety of contexts. To enrich the common core thesis of mysticism and offer insights that could contribute more generally to bridging the gap between...
Lysergic acid diethylamide (LSD) is a potent classic serotonergic psychedelic, which facilitates a variety of altered states of consciousness. Here we present the first meta-analysis establishing dose-response relationship estimates of the altered states of consciousness induced by LSD. Data extracted from articles identified by a systematic literature review following PRISMA guidelines were...
As investigations into the efficacy of psychedelic-assisted psychotherapy to treat depression continue, there is a need to study the possible mechanisms of action that may contribute to the treatment's antidepressant effects. Through a two-round Delphi design, the current study investigated experts' opinions on the psychological mechanisms of action associated with the antidepressant effects of...