The International Journal of Neuropsychopharmacology
September 9, 2026
Friederike Holze, F Müller, Peter Gasser et al.
Abstract Background Anxiety disorders are a major health burden and current treatment options yield unsatisfactory results. Psychedelics, such as lysergic acid diethylamide (LSD) that act via agonism on serotonin 2A receptors, have recently been shown to be effective in the treatment of anxiety symptoms. Aims & Objectives Here, we determine the relationship between the acute experience and...
The International Journal of Neuropsychopharmacology
September 9, 2026
Lisa Harada, K Yonezawa, K Kusudo et al.
Abstract Background Despite sequential treatments with conventional antidepressants, many patients with depression experience insufficient clinical improvement, referred to as treatment-resistant depression (TRD). Psilocybin, a serotonergic psychedelic acting as a 5-HT2A receptor agonist, has attracted increasing attention as a novel treatment, with clinical trials demonstrating rapid and...
The International Journal of Neuropsychopharmacology
September 9, 2026
A Solomon, Y Domany
Abstract Background A critical gap exists in understanding the biological mechanism linking ketamine’s rapid anti-suicidal effects to the Interpersonal Theory of Suicide (IPTS). While the "Kinetic Mismatch" between acute relief and delayed synaptogenesis is well-known, current models overlook how ketamine modulates “Thwarted Belongingness” (a core IPTS pillar) and the attachment anxiety that...
The British Journal of Social Work
September 8, 2026
Alan Maddock, Talal Sultan M. Althobity, Karen McGuigan
Abstract Stress and burnout can have serious negative effects on individual social workers and the organizations they work for. Preliminary evaluations of the Mindfulness-Based Social Work and Self-Care (MBSWSC) programme have found that it reduces stress, burnout, depression, and anxiety and improves the mental well-being of social workers. Building on this evidence, the programme is currently...
American Journal of Clinical Hypnosis
September 4, 2026
Chris E. Corlett, Jesse J. Norris, Sharika Majeti et al.
Mystical experiences or peak spiritual experiences have been shown to be of potential benefit in facilitating personal growth and ameliorating anxiety and depression. A pilot study demonstrated the feasibility of hypnotically induced mystical experiences. Althrough participants' qualitative experiences were recorded and analyzed, they have yet to be reported. Although participants' qualitative...
The International Journal of Neuropsychopharmacology
September 1, 2026
K Kusudo, K Yonezawa, Sota Tomiyama et al.
Abstract Background Psilocybin, a prodrug metabolized to psilocin, a serotonin 2A receptor agonist, has reemerged as a promising therapeutic option for treatment-resistant depression (TRD). Clinical trials conducted mainly in North America and Europe have demonstrated that psilocybin administered with psychological support can produce rapid and sustained antidepressant effects with favorable...
Psychology and Education A Multidisciplinary Journal
August 29, 2026
Honesto “Troi” III Borromeo, Flordelice Pedrera
This study aims to demonstrate that disobedience in Eros and Psyche and Orpheus and Eurydice instead expresses unconscious psychological conflict rooted in desire, repression, and anxiety. Using a Freudian psychoanalytic framework, the analysis applies close textual reading to each myth's pivotal transgressive moment, coding Psyche's lamp scene and Orpheus's backward glance according to the...
Zenodo (CERN European Organization for Nuclear Research)
August 27, 2026
Francisco Javier Meléndez García
preprint
This paper advances a contemporary, neo-Stoic framework for reinterpreting the myth of Sisyphus, transitioning from the traditional existential framework of the absurd toward an ascetic process of metaphysical refinement. Traditionally conceptualized as a tragedy of causal incarceration and futile consciousness, the punitive landscape of Tartarus is here reframed as a structured, pedagogical...
BMC Psychiatry
August 19, 2026
Adam O’Neill, Gillian Haddock, Kate Stalker et al.
Abstract Background Non-affective psychosis is associated with elevated risk of suicide, self-harm, and reduced life expectancy. Symptoms of dissociation are common in non-affective psychosis, and dissociative experiences are known to be linked to multiple markers of elevated clinical risk, including sleep disturbance and negative affect. The present review represents the first comprehensive...
Mindfulness
August 15, 2026
Rosalind McAlpine, Merve Utanğaç, Joanna Kuć et al.
Abstract Objectives Emerging research suggests that meditation may support more beneficial psychedelic experiences while reducing the likelihood of lasting negative effects, yet its specific preparatory benefits remain underexplored. This study aimed to investigate the perceived utility of meditation as a preparatory tool for enhancing positive outcomes and reducing negative effects during...