Alzheimer's disease (AD) is a brain disease with a peculiarity of multiformity and an insidious onset. Multiple-target drugs, especially Chinese traditional medicine, have achieved a measure of success in AD treatment. Evodia rutaecarpa (Juss.) Benth. (Wuzhuyu, WZY, i.e., E. rutaecarpa), a traditional Chinese herb, has been identified as an effective drug to cure migraines. To our surprise, our...
Book Review| August 01 2023 Review: Liquid Light: Ayahuasca Spirituality and the Santo Daime Tradition, by G. William Barnard Liquid Light: Ayahuasca Spirituality and the Santo Daime Tradition. By G. William Barnard. Columbia University Press, 2022. 384 pages. $140.00 hardcover; $35.00 softcover; ebook available. Tarryl Janik Tarryl Janik University of Wisconsin–Milwaukee Search for other works...
Entheogenic natural products (e.g., psylocybin and dimethyltryptamine) are emerging as effective therapeutics to treat debilitating mood disorders that are unresponsive to conventional treatment. The detailed evaluation of psychotropic plants will conceivably lead to the discovery of structurally distinct entheogens that may offer improved or complementary medicinal properties to the classic...
The recent heightened public enthusiasm for the potential therapeutic benefits of psychedelics, especially for treatment-resistant mental health conditions, has resulted in a renewed interest in the underlying science that governs their properties and pharmacology.The science of psychedelics is an intriguing, multi-disciplinary field and encompasses many known psychedelic substances, including...
Advances in Mental HealthJuly 13, 2023Jorge Valdiviezo‐oña, Lizbeth Toscano-Molina, Juan Fernando Chávez et al.4 citations
Objective To map the studies reporting the use of psychedelics in clinical and non-clinical settings by people reporting an eating disorder (ED) and their outcomes.Method To be included, peer-reviewed articles had to be written in English or Spanish and had to address the usage of psychedelics by people reporting an ED. Searches were conducted on PubMed, Scopus, and Web of Science. Data on key...
Traditional psychedelics, such as LSD, psilocybin, or DMT, are psychoactive compounds that exert their effects mainly through agonism over serotonergic receptors. In appropriate doses and contexts, they produce profound changes in the subjective experience, configuring altered states of consciousness that, upon reaching a critical point, involve the appearance of phenomena of mystical,...
The science of psychedelics is an intriguing, multi-disciplinary field that has recently been the subject of heightened public interest. This has mainly resulted from publicity associated with a number of high-profile investigations into psychedelic-assisted therapy for a range of difficult-to-treat mental health conditions. With many psychedelic substances known, including natural,...
Emerging insights from metabolomic-based studies of major depression disorder (MDD) are mainly related to biochemical processes such as energy or oxidative stress, in addition to neurotransmission linked to specific metabolite intermediates. Hub metabolites represent nodes in the biochemical network playing a critical role in integrating the information flow in cells between metabolism and...
Background: The classical psychedelics, psilocybin, peyote, ayahuasca/ N,N-dimethyltryptamine, and lysergic acid diethylamide are considered promising new treatments for psychiatric illnesses, such as depression, anxiety, addiction, and obsessive-compulsive disorders. However, their profound and characteristic subjective effects raise concern for distinctive biases in randomized clinical...
This review of symmetry perception has six parts. Psychophysical studies have investigated symmetry perception for over 100 years (part 1). Neuroscientific studies on symmetry perception have accumulated in the last 20 years. Functional MRI and EEG experiments have conclusively shown that regular visual arrangements, such as reflectional symmetry, Glass patterns, and the 17 wallpaper groups all...