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Depression: all studies

Page 963 of 1,034: studies 9,621 to 9,630 of 10,336, newest first. Back to the depression overview

Research

The experiences of parents in mindfulness-based cognitive therapy.

Clinical Child Psychology and Psychiatry January 2012 Chantal Bailie, Willem Kuyken, Stefanie J. Sonnenberg

Mindfulness-based cognitive therapy (MBCT) is a relatively new intervention that has been developed to help people with recurrent depression stay well in the long term. Although there is evidence that depression impacts negatively on parenting, little is known regarding MBCT's potential impact on parenting. This study used a qualitative design to explore how parents with a history of recurrent...

The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf⁺/⁻ heterozygous null mice.

Neuropharmacology January 2012 Jesse S O Lindholm, Henri Autio, Liisa Vesa et al.

Accumulating evidence suggests that biogenic amine-based antidepressants act, at least in part, via regulation of brain-derived neurotrophic factor (BDNF) signaling. Biogenic amine-based antidepressants increase BDNF synthesis and activate its signaling pathway through TrkB receptors. Moreover, the antidepressant-like effects of these molecules are abolished in BDNF deficient mice....

Signaling pathways underlying the rapid antidepressant actions of ketamine.

Neuropharmacology January 2012 Ronald S. Duman, Nanxin Li, Rong-Jian Liu et al.

Currently available medications have significant limitations, most notably low response rate and time lag for treatment response. Recent clinical studies have demonstrated that ketamine, an NMDA receptor antagonist produces a rapid antidepressant response (within hours) and is effective in treatment resistant depressed patients. Molecular and cellular studies in rodent models demonstrate that...

Mindfulness online: a preliminary evaluation of the feasibility of a web-based mindfulness course and the impact on stress

BMJ Open 2012 Adele Krusche, Eva Cyhlarova, Scott King et al. 120 citations

OBJECTIVES: Stress has been shown to have a number of negative effects on health over time. Mindfulness interventions have been shown to decrease perceived stress but access to interventions is limited. Therefore, the effectiveness of an online mindfulness course for perceived stress was investigated. DESIGN: A preliminary evaluation of an online mindfulness course. PARTICIPANTS: This sample...

Being Mindfully Present in the Moment: Influences on Psychological Functioning

2012 Denise M. Kirby

Mindfulness is defined as a fundamental way of being, a way of relating to all of one‟s experiences whether positive, negative, or neutral, with an attentive, curious, and nonevaluative mindset (Kabat-Zinn, 2003; Williams, Teasdale, Segal, & Kabat-Zinn, 2007). The basic premise underlying mindfulness is that accepting moment-to-moment experiences as they arise, with an open-minded disposition,...

Mindfulness training alters emotional memory recall compared to active controls: support for an emotional information processing model of mindfulness.

Frontiers in Human Neuroscience 2012 Douglas Roberts-Wolfe, Matthew D. Sacchet, Elizabeth Hastings et al. 79 citations

While mindfulness-based interventions have received widespread application in both clinical and non-clinical populations, the mechanism by which mindfulness meditation improves well-being remains elusive. One possibility is that mindfulness training alters the processing of emotional information, similar to prevailing cognitive models of depression and anxiety. The aim of this study was to...

Effects of mindful-attention and compassion meditation training on amygdala response to emotional stimuli in an ordinary, non-meditative state

Frontiers in Human Neuroscience 2012 Gaelle Desbordes, Lobsang Negi, Thaddeus W W Pace et al. 445 citations

The amygdala has been repeatedly implicated in emotional processing of both positive and negative-valence stimuli. Previous studies suggest that the amygdala response to emotional stimuli is lower when the subject is in a meditative state of mindful-attention, both in beginner meditators after an 8-week meditation intervention and in expert meditators. However, the longitudinal effects of...

Mindfulness Based Stress Reduction (MBSR) for Improving Health, Quality of Life, and Social Functioning in Adults

Campbell Systematic Reviews 2012 Michael De Vibe, Arild Bjørndal, Elizabeth Tipton et al. 253 citations

Mind‐body interventions to manage stress‐related health problems are of widespread interest. One of the best known methods is mindfulness‐based stress reduction (MBSR), and MBSR courses are now offered by health services, as well as in social and welfare settings. In this systematic review, we report on the effects of MBSR interventions on health, quality of life, and social functioning. From...

A comparative randomised controlled trial of the effects of brain wave vibration training, iyengar yoga, and mindfulness on mood, well-being, and salivary cortisol.

Evidence-based Complementary and Alternative Medicine December 15, 2011 Deborah Bowden, Claire Gaudry, Seung Chan An et al.

This randomised trial compared the effects of Brain Wave Vibration (BWV) training, which involves rhythmic yoga-like meditative exercises, with Iyengar yoga and Mindfulness. Iyengar provided a contrast for the physical components and mindfulness for the "mental" components of BWV. 35 healthy adults completed 10 75-minute classes of BWV, Iyengar, or Mindfulness over five weeks. Participants were...

A feasibility study of Acceptance and Commitment Therapy for emotional dysfunction following psychosis.

Behaviour Research and Therapy December 2011 Ross G. White, Andrew Gumley, Jackie McTaggart et al.

The experience of psychosis can lead to depression, anxiety and fear. Acceptance and Commitment Therapy (ACT) facilitates individuals to accept difficult mental experiences and behave in ways that are consistent with personally held values. This study was a single (rater) blind pilot randomised controlled trial of ACT for emotional dysfunction following psychosis. Twenty-seven participants with...