Mindfulness
October 1, 2022
Itamar Shapira, Joshua Richman, Thaddeus W W Pace et al.
This study evaluates the effects of treatment with mindfulness-based stress reduction (MBSR) compared to the active control, present-centered group therapy (PCGT), on morning plasma cortisol, interleukin-6 (IL-6), and C-reactive protein (CRP) in veterans diagnosed with post-traumatic stress disorder (PTSD). In a post hoc exploratory analysis, we pooled biomarkers and clinical outcomes of...
JMIR Formative Research
November 14, 2021
Thaddeus W W Pace, Katharine H. Zeiders, S. Cook et al.
Background Firefighters are often exposed to occupational stressors that can result in psychological distress (ie, anxiety and depression) and burnout. These occupational stressors have only intensified with the onset of the COVID-19 pandemic and will likely persist in the postpandemic world. Objective To address occupational stressors confronting firefighters, we pilot tested a novel,...
Frontiers in Human Neuroscience
2012
Gaelle Desbordes, Lobsang Negi, Thaddeus W W Pace et al.
445 citations
The amygdala has been repeatedly implicated in emotional processing of both positive and negative-valence stimuli. Previous studies suggest that the amygdala response to emotional stimuli is lower when the subject is in a meditative state of mindful-attention, both in beginner meditators after an 8-week meditation intervention and in expert meditators. However, the longitudinal effects of...
Psychoneuroendocrinology
February 1, 2010
Thaddeus W W Pace, Lobsang Tenzin Negi, Teresa I Sivilli et al.
Increasing data suggest that meditation impacts stress-related physiological processes relevant to health and disease. For example, our group recently reported that the practice of compassion meditation was associated with reduced innate immune (plasma interleukin [IL]-6) and subjective distress responses to a standardized laboratory psychosocial stressor (Trier Social Stress Test [TSST])....
Psychoneuroendocrinology
2009
Thaddeus W W Pace, Lobsang Tenzin Negi, Daniel D Adame et al.
Meditation practices may impact physiological pathways that are modulated by stress and relevant to disease. While much attention has been paid to meditation practices that emphasize calming the mind, improving focused attention, or developing mindfulness, less is known about meditation practices that foster compassion. Accordingly, the current study examined the effect of compassion meditation...