Mindfulness
October 1, 2022
Itamar Shapira, Joshua Richman, Thaddeus W W Pace et al.
This study evaluates the effects of treatment with mindfulness-based stress reduction (MBSR) compared to the active control, present-centered group therapy (PCGT), on morning plasma cortisol, interleukin-6 (IL-6), and C-reactive protein (CRP) in veterans diagnosed with post-traumatic stress disorder (PTSD). In a post hoc exploratory analysis, we pooled biomarkers and clinical outcomes of...
November 14, 2021
Thaddeus W W Pace, Katharine H. Zeiders, Stephanie H Cook et al.
BACKGROUND Firefighters are often exposed to occupational stressors that can result in psychological distress. These occupational stressors have only intensified with the onset of the COVID-19 pandemic and will likely persist in the post-pandemic world. OBJECTIVE To address occupational stressors confronting firefighters and to improve their well-being, we pilot tested a novel, cost-effective...
JMIR Formative Research
November 14, 2021
Thaddeus W W Pace, Katharine H. Zeiders, S. Cook et al.
Background Firefighters are often exposed to occupational stressors that can result in psychological distress (ie, anxiety and depression) and burnout. These occupational stressors have only intensified with the onset of the COVID-19 pandemic and will likely persist in the postpandemic world. Objective To address occupational stressors confronting firefighters, we pilot tested a novel,...
Trials
April 29, 2019
Thaddeus W W Pace, Sally E Dodds, Alla Sikorskii et al.
Cancer survivors and their informal caregivers (family members, close friends) often experience significant impairments in health-related quality of life (HRQOL), including disruptions in psychological, physical, social, and spiritual well-being both during and after primary cancer treatment. The purpose of this in-progress pilot trial is to determine acceptability and preliminary efficacy (as...
BMJ Open
October 4, 2018
Corina Aguilar-Raab, Marc N Jarczok, Marco Warth et al.
Introduction: Positive social interactions (PSIs) and stable relationships can exert substantial benefits on health. However, patients suffering from depression benefit less from these health-promoting effects. Moreover, relationship quality and even partners' health has been found to be negatively affected by depressive symptomatology, which may result in overall impairments in social...
PLoS One
2018
Deanna M Kaplan, Charles L. Raison, Anne Milek et al.
Mindfulness has seen an extraordinary rise as a scientific construct, yet surprisingly little is known about how it manifests behaviorally in daily life. The present study identifies assumptions regarding how mindfulness relates to behavior and contrasts them against actual behavioral manifestations of trait mindfulness in daily life. Study 1 (N = 427) shows that mindfulness is assumed to...
Frontiers in Human Neuroscience
2012
Gaelle Desbordes, Lobsang Negi, Thaddeus W W Pace et al.
445 citations
The amygdala has been repeatedly implicated in emotional processing of both positive and negative-valence stimuli. Previous studies suggest that the amygdala response to emotional stimuli is lower when the subject is in a meditative state of mindful-attention, both in beginner meditators after an 8-week meditation intervention and in expert meditators. However, the longitudinal effects of...
Psychoneuroendocrinology
February 1, 2010
Thaddeus W W Pace, Lobsang Tenzin Negi, Teresa I Sivilli et al.
Increasing data suggest that meditation impacts stress-related physiological processes relevant to health and disease. For example, our group recently reported that the practice of compassion meditation was associated with reduced innate immune (plasma interleukin [IL]-6) and subjective distress responses to a standardized laboratory psychosocial stressor (Trier Social Stress Test [TSST])....
Psychoneuroendocrinology
2009
Thaddeus W W Pace, Lobsang Tenzin Negi, Daniel D Adame et al.
Meditation practices may impact physiological pathways that are modulated by stress and relevant to disease. While much attention has been paid to meditation practices that emphasize calming the mind, improving focused attention, or developing mindfulness, less is known about meditation practices that foster compassion. Accordingly, the current study examined the effect of compassion meditation...