Recreational nitrous oxide use has grown in popularity among young people and has become a serious public health problem. Chronic use of nitrous oxide can lead to a functional vitamin B12 deficiency and neuropsychiatric complications. This study aimed to investigate the characteristics of neuropsychiatric complications associated with nitrous oxide use and to enhance clinicians' awareness of...
Objective: Responsive neurostimulation (RNS) is a surgical intervention to reduce the frequency of seizures as an adjunctive therapy for patients with drug-resistant epilepsy (DRE). Presurgical neuropsychological evaluations capture symptoms of anxiety and depression, which occur in higher rates within the epilepsy population than in the general population; however, the effects of mood are...
School-based mindfulness interventions in children have shown benefits to child well-being. Here, we investigated the effectiveness of a remote, app-based mindfulness intervention for promoting well-being in children. We conducted a randomized controlled trial (RCT) with two control groups to examine the effects of an 8-week mindfulness intervention in U.S. children ages 8-10. We compared...
Serotonergic hallucinogens also referred to as psychedelics, are psychoactive substances that profoundly alter perception, mood, and cognitive processes. These substances, historically intertwined with religious and cultural rituals, offer profound effects that extend beyond mere hallucinations to profoundly altered states of consciousness. Notable compounds like Lysergic acid diethylamide...
Das inúmeras plantas utilizadas para tratar a depressão, talvez nenhuma seja mais complexa em terminologia e propriedades botânicas do que a ayahuasca. É uma bebida medicinal alucinógena e psicoativa valorizada pelas tribos indígenas amazônicas que se origina da fervura da casca de uma videira chamada Banisteriopis caapi com as folhas de Psycotria viridis. Vários estudos demonstraram a sua...
This paper focuses on the theoretical concept of subjectivity in the translation of metaphors of depressive emotions in W. Styron’s Darkness visible: A memoir of madness into Russian. In his memoir, the author interprets his emotions and names them via metaphors; these interpretations are driven by images in the author’s mind. An image-driven interpretation in translation is a creative act of...
Abstract Psychedelics are compounds acting by serotonin 5-hydroxytryptamine (5-HT) 2A receptor activation and induce several behavioral responses. They are of special interest because of their positive effects on neuropsychiatric disorders (depression and posttraumatic stress disorder). However, several findings revealed that some psychedelic actions are similar to symptoms observed in...
ABSTRACTBackground: Psychedelic substances are increasingly recognized for their therapeutic potential to ease psychological suffering linked to end-of-life issues. However, amid renewed scientific and public interest, policy remains restrictive. Existing reviews have made progress in synthesizing the results of studies of psychedelic interventions, especially psilocybin, and particularly with...
The range of outcomes and published record on the Transcendental Meditation technique across 50 years of research in education, business, and government makes its application unique. Its association with health and relation to an individual’s quality-of-life have also made the technique useful in some developing countries. Data related to application of the technique to higher education in...
Background: The interest in psychoactive agents for treating mental disorders has gathered a growing body of scientific interest. However, research on the relationship between altered states of consciousness (ASCs) and ketamine's antidepressant properties is still limited. Likewise, approaches to sustain early treatment success for the long-term are needed. Taking both aspects into account, the...