The prevalence of stress-induced disorders, including depression, anxiety, posttraumatic stress disorder, and postpartum depression, has been increasing, while current treatment approaches are limited. As a result, researchers are exploring alternative treatments that include ketamine as a prophylactic against these disorders. This review provides an overview of the current knowledge on the use...
This retrospective case study features a woman in her mid-50s who spent her childhood in a religious community plagued by sexual abuse of children. She was abused by her father for more than a decade. The church and her mother ignored her reports about it. In her early twenties, she enrolled herself in the Erhard Seminars Training program that destabilized her, inducing a first-onset psychosis,...
Healthcare work and even studies towards a healthcare profession is associated with a high prevalence of distress. According to recent meta-analyses, half of the medical students worldwide suffer from burn out prior to residency, and 34% of nursing students suffer from depression. The aim of this study was to investigate healthcare students' long-term experiences of mindfulness training, and...
Medicine is taught as a science, but in reality, as with other areas that undergo much public scrutiny, it is often more of an art than a science. Particularly when dealing with controversial areas, physicians often attempt to employ the "standard of care" as a guide to practising medicine, and to protect themselves. However, the standard of care itself is often a reactive and temporary...
Oxytocin (OXT) deficiency is a recently identified novel psycho-neuroendocrine entity associated with anxiety and reduced prosocial behavior. However, diagnosis and clinical progress have been hindered by challenges in reliably measuring OXT. Neurophysin I (NP-I), an equimolarly co-released cleavage product of the OXT precursor peptide, offers a promising alternative biomarker due to its...
Nature-based interventions (NBIs) grounded in mindfulness have been shown to be beneficial for improving mental wellbeing in adults. With increasing mental health challenges among children and adolescents, accessible and cost-effective interventions are essential to enhance their well-being. Brief mindfulness-based NBIs may be helpful in this regard, but there is a dearth of evidence testing...
Compassion is the emotion that motivates people to relieve the physical, emotional, or mental pains of others. Engaging in compassionate behaviour has been found to enhance psychological wellness and resilience. However, constant displays of compassionate behaviour can lead to burnout particularly for healthcare workers who inherently practise compassion day to day. This burnout can be relieved...
Every year the number of poisonings by mushrooms of the genus Amanita increases, especially by species of A. muscaria and A. panterina. These species contain substances that affect the activity of the central nervous system (CNS). The most significant of them are: muscimol, ibotenic acid, muscarine. Muscimol (MUS) and ibotenic acid (IBO) are water–soluble derivatives of isoxazole. They have an...
Psilocybin shows significant therapeutic potential for psilocybin-assisted psychotherapy in addressing various psychiatric conditions. The biosynthetic approach promises rapid and efficient production of psilocybin. Understanding the enzymes that contribute to the biosynthesis of psilocybin can enhance its production process. In this study, we elucidate the crystal structures of...
Quality in SportMarch 21, 2025Kacper Rusiński, Filip Klimas, Dorota Zatłoka-Mazur et al.1 citation
Cannabis is one of the most widely used psychoactive substances globally. In several countries, including Canada, the Netherlands, certain U.S. states, and Australia, its possession is legal. With its growing popularity in recent years, the impact of cannabis on mental health has become a focal point of numerous scientific studies. The aim of this review was to summarize the current...