European Journal of Endocrinology
August 10, 2026
Huma Humayun Khan, Jeremy Tomlinson
Abstract Ketamine is a dissociative anaesthesia which also has analgesic properties and is also used in pain management and depression1. As it produces an out-of-body and rewarding experience, there is a potential danger for abuse of this medication2.Cystitis and cholangiopathy are recognized side effects of ketamine use3,however, published data on ketamine-induced hyponatremia is scarce.The...
European Journal of Endocrinology
August 10, 2026
Ipsita Mishra
Abstract Background Current gender-affirming hormone therapy (GAHT) guidelines are optimized for binary outcomes (full masculinization or feminization), leaving a critical evidence gap for the growing population of non-binary and gender-diverse (NBGD) individuals who seek partial physical changes. These non-traditional therapeutic goals often necessitate the off-label use of low-dose,...
European Journal of Endocrinology
August 1, 2026
Liv-Helen Lang, Sara-Jessica Camerin, Michelle Müller et al.
Patients with arginine vasopressin (AVP) deficiency (formerly central diabetes insipidus) often report social and emotional deficits and heightened anxiety. Growing evidence suggests that these symptoms may, at least partly, reflect concomitant OXT deficiency. OXT plays a key role in increasing empathy and improving emotion recognition. This analysis aimed to examine empathy and emotion...
European Journal of Endocrinology
March 27, 2025
Cihan Atila, Andi Nikaj, Svenja Leibnitz et al.
9 citations
Oxytocin (OXT) deficiency is a recently identified novel psycho-neuroendocrine entity associated with anxiety and reduced prosocial behavior. However, diagnosis and clinical progress have been hindered by challenges in reliably measuring OXT. Neurophysin I (NP-I), an equimolarly co-released cleavage product of the OXT precursor peptide, offers a promising alternative biomarker due to its...
European Journal of Endocrinology
October 1, 1958
A. C. J. Burgers, W. Leemreis, Tadeusz Dominiczak et al.
18 citations
In the last ten years the psychic actions of the drug D-lysergic acid diethylamide LSD-251, delysid (Sandoz Ltd, Basle)] have been extensively studied in man and other mammals. Little work, however, has been done on its action in lower Vertebrates. It was found that in fishes and amphibians the influence of LSD manifests itself in both behaviour- and colour-changes. Besides characteristic...