The multifaceted self refers to how non-clinical individuals perceive themselves as possessing a more sophisticated self-compared to others by accumulating pairs of opposing positive traits. Conversely, depressed individuals are more multifaceted on negative traits, revealing an absence of self-enhancement strategies, which are known to be associated with psychological adjustment. A...
World journal of surgeryMay 1, 2025Shahab Hajibandeh, Christopher R Bowman, Shahin Hajibandeh et al.2 citations
To evaluate the effect of mindfulness-based interventions (MBIs) on psychological outcomes in surgeons. A PRISMA-compliant systematic review and meta-analysis (random effects modeling) was performed searching for comparative studies. Primary outcomes were stress (Perceived Stress Scale, PSS-10) and mindfulness (Cognitive and Affective Mindfulness Scale-Revised, CAMS-R). Secondary outcomes were...
CureusMay 1, 2025Hafiza Wajeeha Waheed, Muhammad R Ashraf, Talha Sajjad et al.
Ketamine has been utilized in various medical contexts, particularly for its effects on the nervous system. Over time, its applications have expanded beyond its initial use, with emerging interest in its potential to influence mood and cognition. In certain clinical populations, it has been associated with a rapid reduction in depressive symptoms and suicidal thoughts, particularly when...
Ketamine, a dissociative anaesthetic, has expanded its clinical use beyond anaesthesia to pain management and treatment-resistant depression. As an N-methyl-d-aspartate receptor antagonist, ketamine disrupts the excitatory neurotransmission via interaction with the opioid, alpha-amino-3-hydroxy-5-methyl-4-isooxazole-propionic acid receptor and serotonin pathways, contributing to its broad...
Integrative medicine use is prevalent among breast cancer survivors to improve lifestyle and manage symptoms associated with cancer or its treatment. This review provides an overview of integrative therapies used for lifestyle improvement and symptom management in breast cancer patients, including diet and exercise recommendations, mind-body approaches including mindfulness-based intervention,...
Patients with refractory conditions often identify themselves with their illness, which affects multiple aspects of their lives. The pictorial representation of illness and self measure (PRISM) is a tool used to assess the enmeshment of individuals' perception of self with a particular medical condition, broadly termed self-condition enmeshment. This study aimed to evaluate changes in PRISM...
Ketamine, a dissociative anesthetic with well documented abuse liability, can also provide rapid-onset and persistent antidepressant effects and is currently used for the management of treatment-resistant depression. Although the precise neurobiological mechanisms underlying its antidepressant actions are not fully determined, a critical feature of ketamine's clinical efficacy may be its...
While most psychedelic substances are considered to carry a relatively low risk of acute or long-term harm, co-use with other psychoactive substances may increase health and social harm. Using a large international survey of adults who use psychedelics, we sought to comprehensively characterize psychedelic co-use. We used data from the 2023 Global Psychedelic Survey, a web-based survey of...
The psychoactive decoction Ayahuasca (AYA) used for therapeutic and religious purposes by indigenous groups and peoples from Amazonian regions produces anti-inflammatory and neuroprotective effects. Thus, it may be useful to attenuate the neuroinflammation and related anxiety- and depressive-like symptoms elicited by inflammatory insults such as sepsis. Rats were pretreated for 3 days with...
Neurobiology of StressMay 1, 2025Alanna Kit, Kate Conway, Savannah Makarowski et al.5 citations
There is growing interest in exploring the therapeutic potential and mechanisms of action of psilocybin on stress-related neuropsychiatric disorders, including depression, generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), addiction, and disordered eating. Despite promising progressions in preclinical and clinical research, the...