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Depression: all studies

Page 489 of 1,034: studies 4,881 to 4,890 of 10,336, newest first. Back to the depression overview

Research

The effects of intensive mindfulness meditation training on mental health: evidence of effectiveness and safety from a matched-controlled intervention study.

Cognitive Behaviour Therapy April 29, 2026 Yuval Hadash, Omer Dar, Romi Oren-Schwartz et al.

Despite increased public interest and research on intensive high-dose mental health interventions, much remains unknown about the mental health effects and safety of multi-day intensive high-dose mindfulness meditation training. Accordingly, we conducted a preregistered prospective intervention study among 89 adults who registered for 6-day insight mindfulness meditation retreats and 46 matched...

DOI: 10.1080/16506073.2026.2656720 (opens in new tab) Full text (opens in new tab) Adverse effects Meditation retreat Meditation safety Mental health +1

Sustaining transformations in psychoanalysis: an interdisciplinary case study on trauma, dreams, and memory reconsolidation

Frontiers in Psychology April 28, 2026 Gilles Ambresin, Tamara Fischmann, Marianne Leuzinger-Bohleber

Chronic depression associated with early trauma remains one of the most treatment-resistant conditions in mental healthcare. Clinical and empirical findings have increasingly suggested that patients with histories of early trauma may benefit differentially from intensive psychoanalytic treatments compared to symptom-focused or short-term psychotherapies. Our conceptual article aims to elucidate...

DOI: 10.3389/fpsyg.2026.1778793 (opens in new tab) Dream Psychoanalytic theory Embodied cognition Learned helplessness +12

The Harmonious Dance: A Narrative Review on Psychedelics and Music in Therapeutic Settings.

Current Neuropharmacology April 28, 2026 Hongshuang Wang, Xiaobing Li, Feng Yu et al.

The integration of psychedelics and music in therapeutic settings is gaining recognition for its potential to enhance mental health outcomes. This review synthesizes current evidence on the neurobiological mechanisms underlying this synergy, focusing on receptor-level pathways (e.g., 5-HT2A receptor agonism, BDNF-TrkB signaling) and neural circuit dynamics (e.g., default mode network...

Mindfulness-Based Interventions in Pediatric Surgical Nursing: A Review of Evidence and Practice

Journal of Pediatric Surgical Nursing April 24, 2026 Kristen Butler

Pediatric surgical nursing is characterized by high clinical acuity, emotional intensity, and significant occupational stressors that contribute to burnout, compassion fatigue, and workforce challenges. Mindfulness-based interventions (MBIs), including Mindfulness-Based Stress Reduction, Mindfulness-Based Cognitive Therapy, and Acceptance and Commitment Therapy, have demonstrated effectiveness...

Effectiveness of Nature-Based Mindfulness Interventions to Improve Mental Health: A Narrative Review.

International Journal of Environmental Research and Public Health April 24, 2026 Costanza Vecchio, Chiara Copat, Paola Rapisarda et al.

Background: Human health is closely interconnected to our ecosystem. Several studies found evidence that nature-based interventions improve mental health. Very recently, these approaches have started including mindfulness practices. Nature-based mindfulness interventions (NBMIs) combine contemplative practices with exposure to natural environments and are increasingly recognised as promising...

DOI: 10.3390/ijerph23050551 (opens in new tab) Full text (opens in new tab) Humans Stress, psychological Mental health Resilience, psychological +4

The role of cytochrome P450 polymorphisms in the pharmacokinetics of oral esketamine.

The pharmacogenomics journal April 24, 2026 Daniël T Coerts, Sanne Y Smith-Apeldoorn, Jérôme C Oude Nijhuis et al.

Oral esketamine displays therapeutic potential for treatment-resistant depression. However, treatment is complicated by a low and variable bioavailability. Genetic polymorphisms in the cytochrome P450 (CYP) enzymes responsible for esketamine's metabolism may influence bioavailability. In a subsample of patients included in a placebo-controlled trial investigating repeated, low dose oral...

Distinct Roles of Therapeutic Expectations and Dissociative Symptoms in Antidepressant Response During Ketamine Treatment in Routine Care

medRxiv Preprint Server April 23, 2026 Willys Cantenys, Zeynep Yoldas, Luc Masset et al. preprint

Background Ketamine is a rapid-acting antidepressant that produces acute dissociative symptoms. In routine care, the respective contributions of therapeutic expectations and dissociative symptoms to antidepressant response, and the directionality of their associations with depressive symptom change, remain poorly characterized.

Enhancing psychological performance and basketball skills: a comparative study of elite athletes and college recreational players after an 8-week mindfulness intervention.

Frontiers in Psychology April 22, 2026 Qi-Fan Wu, Jia-Qi Du

Background: In high-intensity sports such as basketball, psychological factors significantly influence performance. Mindfulness-based interventions (MBIs) show potential for reducing anxiety, depression, and mental fatigue while enhancing attention, resilience, and basketball technical skills. However, few studies have compared the effects of MBI between elite athletes and recreational players....

DOI: 10.3389/fpsyg.2026.1794656 (opens in new tab) Full text (opens in new tab) Comparative study Mental training Mindfulness intervention Basketball skills +1

Efektivitas Terapi Murottal Al-Quran dan Meditasi terhadap Kesehatan Mental untuk Remaja dengan Adiksi Smartphone

Nutrix Journal April 22, 2026 Rosyidah Alfitri, Rani Safitri, N. Keswara

Adolescents are vulnerable to mental health disorders resulting from excessive smartphone use, which can trigger stress, anxiety, and depression, as well as affect behavior and psychological well-being. This study examined the effectiveness of a combination of murottal Al-Qur’an therapy and meditation on the mental health of adolescents with smartphone addiction using a quasi-experimental...

Mindfulness research in Saudi Arabia: a scoping review of mental health applications in a non-WEIRD context

Middle East Current Psychiatry April 22, 2026 Hanan Alfayez

Abstract Background Mindfulness-based approaches have gained increasing attention in mental health research and clinical practice. However, most empirical evidence on mindfulness has been generated in Western populations, with comparatively limited synthesis of research conducted in non-WEIRD contexts. Aims This scoping review aims to map and synthesize existing research on mindfulness...

DOI: 10.1186/s43045-026-00633-2 (opens in new tab) Full text (opens in new tab) Mindfulness Mental health Psychological intervention Context archaeology +9