Research Square
September 30, 2026
Merve Mollaahmetoglu, Joy Krecké, Charlie Oldfield et al.
preprint
Abstract Ketamine is known to have anti-depressant effects and is suggested to reduce substance use. However, little is known about the mechanism of these effects. Given evidence from studies in depression of a greater therapeutic effect in those with a family history of AUD, this latter factor was also investigated as a moderating factor. We used data from the KARE trial, a randomised...
Journal of Personalized Medicine
September 30, 2026
Joshuan J. Barboza, Alma Delia Santiago Mijangos, Junior Smith Torres-Román et al.
Background/Objectives: Psychological distress, anxiety, depressive symptoms and fear of cancer recurrence affect many women treated for breast cancer and often persist beyond active treatment. Mindfulness-based cognitive therapy (MBCT) is manualised and can be delivered in groups or over the internet, which makes it a candidate component of personalised supportive care, but its effect has not...
Zenodo (CERN European Organization for Nuclear Research)
September 30, 2026
Jagdish Appasaheb Sardesai, Amol Appaso Kamble
preprint
Abstract Generation Z is navigating profound challenges defined by an unprecedented mental health crisis, reporting the highest rates of stress, anxiety, and depression among age groups. As the first true digital natives, they grapple with the dual-edged sword of technology, where constant connection and social media exposure contribute to feelings of inadequacy and isolation. By investigating...
Mindfulness
September 30, 2026
Yoel A. Behar, Yuval Hadash, Omer Dar et al.
Abstract Objective We aimed to test whether mental health problems are associated with distressing experiences during intensive meditation training and with the impact of these experiences following intensive training. Method We conducted a preregistered prospective matched-control study comparing 6-day insight mindfulness meditation retreats ( n = 89) to daily living among matched controls ( n...
Journal of Holistic Nursing
September 30, 2026
N. Sanmamed Salgado, Tereza Maria Mendes Diniz de Andrade Barroso, Maria Isabel Marques et al.
" Program, a Reiki-informed meditative intervention for first-year nursing students, and to estimate pre-post change in distress and well-being.DesignSingle-group pretest-posttest pilot feasibility study.MethodsInformed by Transitions Theory and holistic nursing, a seven-session hybrid program combined the spiritual precepts of Reiki with Joshin Kokyu Ho breathing meditation and guided imagery;...
September 30, 2026
Abraham Peled
preprint
AbstractPsychiatry is the only branch of medicine that still diagnoses without reference to the organ it treats. Psychiatry: The Case for Starting Over argues that this is a structural failure rather than a temporary gap. The descriptive nosology inherited from Kraepelin and formalized in the DSM achieved diagnostic reliability at the cost of validity. Its categories were assembled by committee...
Sleep Epidemiology
September 29, 2026
Yuki Tanaka, Yuichiro Otsuka, Suguru Nakajima et al.
Dream experiences have been associated with emotional and mental health characteristics; however, epidemiological evidence among adolescents remains limited. This study examined dream experiences and their associations with sleep, mental health, and lifestyle factors among students from participating high schools in one prefecture in western Japan. A school-based, non-random, cross-sectional...
September 29, 2026
Paul S. Links
Considere la neuromodulación para pacientes con TLP y depresión mayor comórbida que no hayan respondido a antidepresivos y otros medicamentos. La evidencia de revisiones sistemáticas respalda un papel complementario en estos casos. Al usar ketamina en el TLP, vigile cuidadosamente la aparición de conductas desinhibidas y el aumento de la ideación suicida. Los reportes de casos han documentado...
September 29, 2026
Paul S. Links
Envisagez la neuromodulation pour les patients atteints de trouble de la personnalité borderline présentant une dépression majeure comorbide et un échec des antidépresseurs et d'autres médicaments. Les données d'une revue systématique soutiennent un rôle complémentaire dans ces cas. Lors de l'utilisation de la kétamine dans le trouble de la personnalité borderline, surveillez attentivement les...
September 29, 2026
Paul S. Links
Considere a neuromodulação para pacientes com TPB e depressão maior comórbida que não responderam a antidepressivos e outras medicações. Evidências de revisões sistemáticas apoiam um papel complementar nesses casos. Ao utilizar cetamina no TPB, monitore cuidadosamente comportamentos desinibidos e aumento da ideação suicida. Relatos de caso documentaram ambas as reações como efeitos negativos. A...