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Depression: all studies

Page 198 of 1,034: studies 1,971 to 1,980 of 10,336, newest first. Back to the depression overview

Research

The effect of mindfulness-based stress reduction (MBSR) training on serum cortisol levels, depression, stress, and anxiety in type 2 diabetic older adults during the COVID-19 outbreak

Journal of Medicine and Life December 1, 2022 A. Sayadi, Seyed Hamid Seyed Bagheri, A. Khodadadi et al.

Old age is rapidly increasing and is linked to with chronic diseases, especially diabetes. Diabetes is associated with increased anxiety, stress, and depression and, in turn, can increase cortisol secretion. To this end, the present research studied the impact of mindfulness-based stress reduction (MBSR) training on serum cortisol levels, depression, anxiety, and stress in type 2 diabetic...

Mindfulness on Rumination in Patients with Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

International Journal of Environmental Research and Public Health December 1, 2022 Pan Li, Lingyun Mao, Maorong Hu et al.

Objective: To systematically evaluate the effectiveness of mindfulness-based interventions (MBIs) on rumination among patients with depression and their efficacy across countries and year of publication and control conditions. Methods: Web of Science Core Collection, Medline, BIOSIS Citation Index, KCI-Korean Journal Database, SciELO Citation Index, PubMed, Cochrane Library, and Embase were...

Increased insula response to interoceptive attention following mindfulness training is associated with increased body trusting among patients with depression.

Psychiatry Research Neuroimaging December 1, 2022 Michael Datko, Jacqueline Lutz, Richa Gawande et al.

Interoceptive dysfunction is often present in anxiety and depression. We investigated the effects of an 8-week intervention, Mindfulness Training for Primary Care (MTPC), on brain mechanisms of interoceptive attention among patients with anxiety and/or depression. We hypothesized that fMRI brain response to interoception in the insula, a region known for interoceptive processing, would increase...

The association between stage of treatment-resistant depression and clinical utility of ketamine/esketamine: A systematic review.

Journal of Affective Disorders December 1, 2022 Anastasia Levinta, Shakila Meshkat, Roger S McIntyre et al.

Ketamine has demonstrated rapid and significant antidepressant effects in patients with treatment resistant depression (TRD). Herein, we conducted a systematic review to determine ketamine's efficacy as a function of the stage of treatment resistance (e.g., number of failed treatments) among individuals with TRD. A systematic search of PubMed and Scopus from inception to August 2021 was...

Intravenous Ketamine for Late-Life Treatment-Resistant Depression: A Pilot Study of Tolerability, Safety, Clinical Benefits, and Effect on Cognition

American Journal of Geriatric Psychiatry December 1, 2022 H. Oughli, M. A. Gebara, A. Ciarleglio et al. 33 citations

Objective: Evidence-based treatment options for late-life treatment-resistant depression (TRD) are limited. Ketamine is a promising treatment for TRD; however, there is a paucity of data on its safety and efficacy in older adults. Methods: In this pilot clinical trial, 25 adults aged ≥60 years with TRD received IV ketamine openly twice a week for 4 weeks; partial responders at the end of this...

A unique case of very low‐dose subcutaneous ketamine use: Maintenance option of ketamine for treatment‐resistant depression

Clinical Case Reports December 1, 2022 Adem T. Can, Daniel F. Hermens, Jim Lagopoulos 6 citations

Abstract Numerous studies have demonstrated that low‐dose subanesthetic intravenous ketamine infusion treatment leads to rapid improvement of treatment‐resistant depression. The following case report describes the use of a very low‐dose subcutaneous ketamine as a form of maintenance in a patient with severe treatment‐resistant depression using a retrospective chart review.

Efficacy and Safety of Esketamine Combined with Antidepressants for Treatment-Resistant Depression: A Meta-Analysis

Neuropsychiatric Disease and Treatment December 1, 2022 Peng Liu, Shanshan Zhang, Yun Liang et al. 16 citations

Objective: To evaluate the efficacy and safety of esketamine + antidepressant in treatment-resistant depression. Methods: We searched PubMed, Web of Science, Embase, CNKI, and Wanfang databases to obtain published information on esketamine + antidepressant from inception to July 2022. We searched for randomized controlled studies on the treatment of depression with a double-blind induction...

DOI: 10.2147/ndt.s388764 (opens in new tab) Treatment-resistant depression Meta-analysis Antidepressant Depression economics +3

A Chain Mediation Model Reveals The Association Between Mindfulness and Depression of College students

Research Square November 29, 2022 Junliang Zhang, Shuang Zheng, Zhongzheng Hu et al. preprint

The study aims to explore the relationship among mindfulness, depression, meaning in life (MIL) and psychological resilience (PR), and verify whether MIL and PR have a chain mediating effect between mindfulness and depression .1034 college students in a province were investigated by using Adolescent Mindfulness Scale, Depression Scale, Meaning in Life Scale and Psychological Resilience Scale....

Changes in music-evoked emotion and ventral striatal functional connectivity after psilocybin therapy for depression

Journal of Psychopharmacology November 26, 2022 Melissa Shukuroglou, Leor Roseman, David Nutt et al. 38 citations

Background: Music listening is a staple and valued component of psychedelic therapy, and previous work has shown that psychedelics can acutely enhance music-evoked emotion. Aims: The present study sought to examine subjective responses to music before and after psilocybin therapy for treatment-resistant depression, while functional magnetic resonance imaging (fMRI) data was acquired. Methods:...

Mindfulness Prevents Depression and Psychopathology in Elderly People with Mild to Moderate Alzheimer’s Disease: A Randomized Clinical Trial

Journal of Alzheimer's Disease November 24, 2022 Domingo J Quintana-Hernández, Jaime Rojas-Hernández, Ángelo Santana Del Pino et al.

Background: This longitudinal study addressed whether mindfulness practice prevents psychological and behavioral symptoms, especially mood disorders, in Alzheimer’s disease (AD). Objective: To assess the incidence of depression in the course of AD and to determine which non-pharmacological treatment (NPT) is most effective in preventing psychopathological symptoms. Methods: We conducted a...