Clinical Case Reports
April 4, 2021
Terry Schwartz, Mary Ellen Trunko, David Feifel et al.
52 citations
Severe and enduring eating disorders carry the highest mortality rate of all psychiatric illnesses, especially when combined with treatment-resistant depression. Four patients with both conditions received repeated ketamine treatments over 12 or more months. Depression improved, but eating disorder symptoms changed only modestly.
Clinical Case Reports
September 1, 2024
David S Jevotovsky, Harman Chopra, Court Wing et al.
9 citations
A single patient with complex regional pain syndrome (CRPS) that did not respond to standard treatments experienced substantial pain relief and improved function after taking psilocybin. This case suggests psilocybin may be a promising therapy for refractory CRPS, but more research is needed to determine its effectiveness and the best dosage for chronic pain.
Clinical Case Reports
November 27, 2021
Palash Kumar Bose, Debika Ray, Prodip Biswas et al.
8 citations
Lysergic acid diethylamide (LSD) is a potent hallucinogenic drug that alters mood and perception. Although self-inflicted cut-throat wounds and other self-harm injuries caused by LSD are extremely rare, recent reports indicate such behaviors are emerging, potentially complicating assessments in forensic psychiatry.
Clinical Case Reports
May 28, 2024
Harman Chopra, Tim Furnish, Monica Verduzco-Gutierrez et al.
6 citations
A 41-year-old fully vaccinated woman with Long-COVID syndrome experienced significant symptom relief after self-medicating with psilocybin and MDMA. Long-COVID, a condition persisting after the acute phase of COVID-19, currently lacks effective holistic treatments. This case suggests potential benefit from these substances, but further research is required to evaluate their safety and efficacy.
Clinical Case Reports
December 1, 2022
Adem T. Can, Daniel F. Hermens, Jim Lagopoulos
6 citations
A single patient with severe treatment-resistant depression received maintenance therapy with very low-dose subcutaneous ketamine, following initial improvement with intravenous ketamine. A retrospective chart review showed that this approach sustained the antidepressant response without significant side effects, suggesting a potential alternative maintenance strategy for patients who respond to intravenous ketamine but require ongoing treatment.
Clinical Case Reports
June 1, 2024
Nava Raj Sharma, Arjun Basnet, Saral Lamichhane et al.
4 citations
Chronic ketamine use can cause sphincter of Oddi dysfunction (SOD), leading to hepatobiliary complications such as cholestasis, biliary sepsis, and even death. A case of a 29-year-old woman with upper abdominal pain from SOD due to chronic ketamine abuse is presented. Ketamine induces SOD by activating muscarinic receptors in the sphincter of Oddi, obstructing or impairing bile and pancreatic ducts. Taking a detailed substance abuse history is crucial for early identification of ketamine-induced SOD. Early treatment can prevent permanent liver and pancreas damage.
Clinical Case Reports
August 30, 2024
Seragnoli Federico, Martignoni Geo, Martignoni Entela et al.
3 citations
A patient with throat cancer and severe existential distress safely received psychedelic-assisted therapy at home. The patient tolerated the intervention well and reported on measures of anxiety, depression, and distress. This single-case study aligns with previous findings suggesting that psychedelic-assisted therapy can be safely applied to potentially relieve existential distress in people with life-threatening conditions. Because this is one case, generalizations require caution; placebo effects, expectancy, and the natural course of illness may influence outcomes. Controlled trials are needed to confirm efficacy and safety in diverse settings.
Clinical Case Reports
September 1, 2024
Swotantra Gautam, Aakash Neupane, Ivonne De La Hoz Molina et al.
1 citation
MDMA and cocaine can cause rhabdomyolysis that begins suddenly, but delayed-onset rhabdomyolysis also occurs and its underlying mechanisms are concerning. Early treatment improves outcomes; patients with such cases should be quickly transferred to and treated in hospitals with intensive care and kidney replacement therapy capabilities.
Clinical Case Reports
March 1, 2023
Bruno Pedraz-Petrozzi, Michael Deuschle, Maria Gilles
A 42-year-old patient with severe treatment-resistant depression and psychiatric comorbidities attempted suicide five weeks after hospital admission. After starting dextromethorphan/bupropion, her mood improved and suicide risk decreased, allowing discharge.