Movement DisordersFebruary 2024Kyoungwon Baik, Yae Ji Kim, Mincheol Park et al.
Minor hallucinations (mHs) and well-structured major hallucinations (MHs) are common symptoms of Parkinson's disease (PD) psychosis. To investigate the resting-state networks (RSNs) in patients with PD without hallucinations (PD-nH), with mH (PD-mH), and with MH (PD-MH). A total of 73 patients with PD were enrolled (27 PD-nH, 23 PD-mH, and 23 PD-MH). Using seed-based functional connectivity...
Meditation practices have demonstrated numerous psychological and physiological benefits, yet capturing the neural correlates of varying meditative depths remains challenging. This study aimed to decode self-reported time-varying meditative depth in expert practitioners using EEG. Expert Vipassana meditators (n=34) participated in two separate sessions. Participants reported their meditative...
Mind-wandering is a frequent, daily mental activity, experienced in unique ways in each person. Yet neuroimaging evidence relating mind-wandering to brain activity, for example in the default mode network (DMN), has relied on population-rather than individual-based inferences due to limited within-individual sampling. Here, three densely-sampled individuals each reported hundreds of...
Ketamine administration leads to a psychotomimetic state when taken in large bolus doses, making it a valid model of psychosis. Therefore, understanding ketamine's effects on brain functioning is particularly relevant. This meta-analysis focused on neuroimaging studies that examined ketamine-induced brain activation at rest and during a task. Included are 10 resting-state studies and 23...
Chronic loneliness is a risk factor for physical and health problems, in part due to dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system. In contrast, temporary moments of positive solitude (passing good times alone and not feeling lonely) appear to have positive effects on mental health, social life, and creativity, and seems to be a buffer against...
Mindfulness training has been shown to promote positive mental health outcomes and related changes in neural networks such as the default mode network, which has a central node in the posterior cingulate cortex (PCC). Previous work from our group reported on the impact of a novel, neurofeedback augmented mindfulness training (NAMT) task on regulation of PCC hemodynamic activity in typically...
We review and synthesize recent religion and brain studies and find that at a broad network neuroscience level, religious/spiritual experiences (RSEs) appear to depend crucially upon interactions between the default mode network (DMN), the frontoparietal network (FPN), and the salience network (SN). We see this general result as broadly consistent with Menon's et al. "Triple Network or...
Until recently, understanding the neurobiology of dreaming has relied upon on correlating a subjective dream report with a measure of brain activity or function sampled from a different occasion. As such, most assumptions about dreaming come from the neuroscience of rapid eye-movement (REM) sleep from which many, but not all, dream reports are recalled. Core features of REM sleep (intense...
The PD-DLB psychosis complex found in Parkinson's disease (PD) and Dementia with Lewy Bodies (DLB) includes hallucinations, Somatic Symptom/Functional Disorders, and delusions. These disorders exhibit similar presentation patterns and progression. Mechanisms at the root of these symptoms also share similarities with processes promoting altered states of consciousness found in Rapid Eye Movement...
Independent component analysis (ICA) is one of the leading approaches for studying brain functional networks. There is increasing interest in neuroscience studies to investigate individual differences in brain networks and their association with demographic characteristics and clinical outcomes. In this work, we develop a sparse Bayesian group hierarchical ICA model that offers significant...