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Stefano Delli Pizzi

4 papers in the library · 87 citations · publishing 2023-2026

Papers

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A Shared Entropic Axis Spans States of Consciousness Across Pharmacological and Clinical Conditions

bioRxiv Preprint Server June 12, 2026 Dante Sebastián Galván Rial, Gabriel A. Della Bella, Lorina Naci et al. preprint

A general account of how diverse states of consciousness arise from brain activity requires a quantitative framework that generalises across them. The Entropic Brain Theory proposes that states of consciousness can be ordered along a single dimension defined by the entropy of spontaneous neural activity, but this prediction has not been tested across pharmacological and clinical perturbations...

The central role of the Thalamus in psychosis, lessons from neurodegenerative diseases and psychedelics.

Transl Psychiatry December 13, 2023 Marco Onofrj, Mirella Russo, Stefano Delli Pizzi et al. 42 citations

The PD-DLB psychosis complex found in Parkinson's disease (PD) and Dementia with Lewy Bodies (DLB) includes hallucinations, Somatic Symptom/Functional Disorders, and delusions. These disorders exhibit similar presentation patterns and progression. Mechanisms at the root of these symptoms also share similarities with processes promoting altered states of consciousness found in Rapid Eye Movement...

LSD-induced changes in the functional connectivity of distinct thalamic nuclei.

Neuroimage December 1, 2023 Stefano Delli Pizzi, Piero Chiacchiaretta, Carlo Sestieri et al. 27 citations

The role of the thalamus in mediating the effects of lysergic acid diethylamide (LSD) was recently proposed in a model of communication and corroborated by imaging studies. However, a detailed analysis of LSD effects on nuclei-resolved thalamocortical connectivity is still missing. Here, in a group of healthy volunteers, we evaluated whether LSD intake alters the thalamocortical coupling in a...

Spatial Correspondence of LSD-Induced Variations on Brain Functioning at Rest With Serotonin Receptor Expression.

Biological psychiatry. Cognitive neuroscience and neuroimaging July 1, 2023 Stefano Delli Pizzi, Piero Chiacchiaretta, Carlo Sestieri et al. 18 citations

Lysergic acid diethylamide (LSD) is an atypical psychedelic compound that exerts its effects through pleiotropic actions, mainly involving 1A/2A serotoninergic (5-HT) receptor subtypes. However, the mechanisms by which LSD promotes a reorganization of the brain's functional activity and connectivity are still partially unknown. Our study analyzed resting-state functional magnetic resonance...