Children
December 22, 2022
Saral R. Desai, Vidisha Jain, Sona Xavier et al.
(1) Objectives: Hallucinogens are being explored as a potential treatment of psychiatric disorders. Micro dosing of illicitly purchased hallucinogen drugs is on the rise despite conclusive benefits. We aimed to evaluate the prevalence and odds of hopelessness, suicidality, and co-occurring substance use among adolescent hallucinogen users. (2) Methods: We performed a retrospective analysis of...
JAMA Psychiatry
December 7, 2022
Joshua S. Siegel, James E. Daily, Demetrius Perry et al.
168 citations
Importance Psychedelic drugs are becoming accessible in the US through a patchwork of state legislative reforms. This shift necessitates consensus on treatment models, education and guidance for health care professionals, and planning for implementation and regulation. Objective To assess trends in psychedelics legislative reform and legalization in the US to provide guidance to health care...
Neuroscience & Biobehavioral Reviews
December 2022
Andrea J Narayan, Luke A. Downey, Brooke Manning et al.
Cannabidiol's (CBD) safety profile and broad action has made it a popular treatment option for anxiety and co-occurring sleep disturbance. However, its efficacy in healthy and clinical populations, treatment duration, formulation and doses for optimal therapeutic benefits remains unclear. Selected databases were examined from inception to October 2022. Study selection, data extraction and...
Molecular Pharmacology
December 2022
Taryn Bosquez-Berger, Sierra Wilson, Christos Iliopoulos-Tsoutsouvas et al.
The two main constituents of cannabis are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). While Δ9-THC pharmacology has been studied extensively, CBD-long considered inactive-is now the subject of vigorous research related to epilepsy, pain, and inflammation and is popularly embraced as a virtual cure-all. However, our understanding of CBD pharmacology remains limited, although CBD...
Vigilância Sanitária em Debate
November 30, 2022
Juliana Pereira Lopes, Julino Assunção Rodrigues Soares Neto, Fúlvio Rieli Mendes
Introdução: A internet é um dos principais meios para o compartilhamento de informações, além de ser uma plataforma com recursos para o comércio on-line.Recentemente tem-se observado um aumento no interesse e consumo de substâncias psicotrópicas de origem natural, seja em um contexto religioso, cultural ou hedonístico.Objetivo: Avaliar se as informações sobre psicotrópicos de origem natural...
Revista de Neuro-Psiquiatría
November 2, 2022
Laura Alcantarilla, Enrique García-alcarria, Celia Almonacid
3 citations
La ayahuasca pertenece al grupo de alucinógenos de origen vegetal con los que comparte su capacidad de alterar el estado de conciencia y provocar alteraciones perceptivas. Empleada tradicionalmente en forma de brebaje en ritos ceremoniales con el propósito de alcanzar experiencias de contenido espiritual o sanatorio, su uso se ha extendido a lo largo de centurias hasta nuestro actual contexto...
Neuropharmacology
November 1, 2022
Regina Pacitto, Craig A Peters, Allesandra Iadipaolo et al.
Emotion dysregulation is considered a core component of posttraumatic stress disorder (PTSD). Cognitive reappraisal is one therapeutic emotion regulation strategy that has been widely studied among individuals with mood and anxiety disorders, and numerous differences in brain activation patterns have been shown between individuals with and without PTSD during tasks of cognitive reappraisal....
Cureus
October 31, 2022
Arafath Mohamed, Shehla Touheed, Muzammil Ahmed et al.
11 citations
Post-traumatic stress disorder (PTSD) is a significant public health concern for which existing therapies are only marginally effective. Indisputably, the primary line of treatment for PTSD is psychotherapy, according to current treatment guidelines. However, PTSD continues to be a chronic condition even after psychotherapy, with high psychiatric and medical illness rates. There is a dire need...
October 26, 2022
George Danias, Jacob Appel
BACKGROUND Psychedelic substances have demonstrated promise in the treatment of depression, anxiety, and substance use disorders. Significant media coverage has been dedicated to psychedelic medicine, but it is unclear whether the public associates psilocybin with its potential therapeutic benefits. The COVID-19 pandemic led to an increase in depression, anxiety, and substance abuse in the...
BCP Social Sciences & Humanities
October 18, 2022
Anastasia Liu
Drugs both heal and destroy the human body and mind. Illegal drugs such as heroin, LSD, cocaine and marijuana were often celebrated as means to literary insight. In the 1960s drugs were used by the Beat writers, notably Allen Ginsberg, who referred to them in his poetry as a means to both political and spiritual insight. However, drugs also proved to be a dangerous and destructive addiction....