Medicina
May 9, 2023
Gniewko Więckiewicz, Julia Marek, Iga Stokłosa et al.
5 citations
Background and Objectives: PolDrugs is the largest Polish naturalistic nationwide survey to present basic demographic and epidemiological data that could potentially prevent harm from illicit substances intake in drugs users. The most recent results were presented in 2021. The goal of this year’s edition was to re-present the above data and compare it to the previous edition’s data to identify...
Australian & New Zealand Journal of Psychiatry
May 6, 2023
Julia Lappin, Shane Darke, Michael Farrell
Australian & New Zealand Journal of Psychiatry, 57(6) Interest in prescribing psychoactive drugs as treatments for mental health conditions has been highlighted recently by the decision by the Therapeutic Goods Administration (TGA) to permit, from 1 July 2023, authorised psychiatrists to prescribe medicines containing psilocybin for treatment-resistant depression and...
Psychiatry Research
May 1, 2023
Kirsten R Müller-vahl, Anna Pisarenko, Natalia Szejko et al.
36 citations
Preliminary data suggest that cannabis-based medicines might be a promising new treatment for patients with Tourette syndrome (TS)/chronic tic disorders (CTD) resulting in an improvement of tics, comorbidities, and quality of life. This randomized, multicenter, placebo-controlled, phase IIIb study aimed to examine efficacy and safety of the cannabis extract nabiximols in adults with TS/CTD (n =...
International Journal of Drug Policy
May 1, 2023
Joseph J Palamar, Austin Le, Charles M Cleland et al.
41 citations
Drug use is prevalent among people who attend electronic dance music (EDM) parties at nightclubs or festivals. This population can serve as a sentinel population to monitor trends in use of party drugs and new psychoactive substances (NPS) that may diffuse through larger segments of the population. We surveyed adults entering randomly selected EDM parties at nightclubs and dance festivals in...
Psychotropes
April 21, 2023
Pierre Poloméni
Les adolescents et jeunes adultes participant à des événements musicaux consomment fréquemment des substances psychoactives pour améliorer la qualité des relations et des perceptions. Parmi ces substances, une association de LSD puis de MDMA, prises à une heure d’intervalle, dénommée Candy Flip, connue depuis longtemps, bénéficie d’une bonne réputation. Notre travail explore ces substances en...
bioRxiv : the preprint server for biology
April 11, 2023
Shinnyi Chou, Kenneth N Fish, David A Lewis et al.
preprint
Individuals with schizophrenia are at elevated genetic risks for comorbid cannabis use, and often experience exacerbations of cognitive and psychotic symptoms when exposed to cannabis. These findings have led a number of investigators to examine cannabinoid CB1 receptor (CB1R) alterations in schizophrenia, though with conflicting results. We recently demonstrated the presence of CB1R in both...
AJOB Neuroscience
April 3, 2023
Hojjat Soofi, C. Forlini
Carhart-Harris, R., B. Giribaldi, R. Watts, M. Baker-Jones, A. Murphy-Beiner, R. Murphy, J. Martell, A. Blemings, D. Erritzoe, D. J. Nutt, et al. 2021. Trial of psilocybin versus escitalopram for depression. New England Journal of Medicine 384 (15):1402–11. doi:10.1056/NEJMoa 2032994. Coulson, A. 2023. Lecanemab approved for use by US FDA. NeuroCentral, 19 Jan. https://www.neuro-central.com/...
Cannabis and Cannabinoid Research
April 2023
Nicole A Lookfong, Wesley M Raup-Konsavage, Yuval Silberman
Background: The endocannabinoid (eCB) system plays an important role in homeostatic regulation of anxiety and stress responses; however, the eCB system can be disrupted following traumatic stressors. Additionally, traumatic or chronic stressors that occur during adulthood or early life can cause long-lasting disturbances in the eCB system. These alterations interfere with...
Diagnostics
March 10, 2023
Liliana Dragomir, Virginia Marina, Mihaela Anghele et al.
MDMA (3,4-methylenedioxymethamphetamine; commonly referred to as “Molly” or “ecstasy”) is a synthetic compound, structurally and pharmacologically similar to both amphetamines and mescaline. MDMA differs somewhat from traditional amphetamines in that it is not structurally similar to serotonin. Cocaine is rare and cannabis is consumed less frequently than in Western Europe. Heroin is the drug...
Current Psychiatry
March 1, 2023
Marija S. Marković
1 citation
Savvy Psychopharmacology M r.D, age 41, presents to the emergency department (ED) with altered mental status and suspected intoxication.His medical history includes alcohol use disorder and spinal injury.Upon initial examination, he is confused, disorganized, and agitated.He receives IM lorazepam 4 mg to manage his agitation.His laboratory workup includes a negative screening for blood alcohol,...