Pharmakopsychiatrie, Neuro-Psychopharmakologie
September 1978
M Koukkou, D Lehmann
The study investigates EEG characteristics in relation to psychopathology. Tetrahydro-Cannabinol (THC) was taken orally by 12 volunteers. The EEG was recorded continuously, and THC-induced psychopathology was assessed by pre- and post-experiment questionnaires. Subjects had to signal THC experiences. EEG measurements (distribution means of frequency bands derived from EEG frequency analysis)...
International Journal of the Addictions
August 1978
T F Babor, J H Mendelson, B Uhly et al.
Adult male volunteers with a prior history of either moderate (N = 12) or heavy (N = 14) marijuana use were systematically observed before, during, and after a 21-day period of free access to marijuana cigarettes. Data relevant to social interaction and recreational preferences were collected at hourly intervals. Moderate users consumed an average of 2.6 cigarettes per day and showed both acute...
The British Journal of Psychiatry
May 1978
S S Menhiratta, N N Wig, S K Verma
Fifty persons who had all been heavy cannabis users for a long time were given psychological tests measuring psychomotor, perceptual and other variables. Half of these persons were "Charas" smokers, half "Bhang" drinkers. The duration of cannabis use was 4--10 years, with an average daily dose of 150 mg tetrahydrocannabinol. A matched control group of twenty-five persons were given the same...
Psychiatry
May 1978
I D Rinder
BECAUSE OF MARIJUANA'S apparent widespread and growing use, and possible future decriminalization, there is understandable concern about the effects of marijuana on behavior. However, in any serious deliberation about effects on behavior, two divergent views are equally unacceptable: that of the naive medical moralizer, who believes that marijuana turns people into vicious criminals; and that...
Cellular and Molecular Life Sciences
March 1, 1978
Greg Went
43 citations
Using the micronucleus test as a screening method for mutagenic activity, no significant increase in the number of micronuclei was found when LSD, psilocybin or delta 9-THC were administered in 3 logarithmically increasing doses to mice, Azathioiprine (Imuran), given as a positive control, caused a statistically significantt increase in the micronucleated cells.
Medicina e historia
October 1, 1977
T. Thoresen
VERA RUBIN (editor), Cannabis and culture, The Hague and Paris, Mouton, 1975, 8vo, pp. xiv, 598, illus., $24.95. TIMOTHY H. H. THORESEN (editor), Toward a science of man. Essays in the history of anthropology, The Hague and Paris, Mouton, 1975, 8vo, pp. xiv, 232, $14.95. The Ninth International Congress of Anthropological and Ethnological Sciences was held in Chicago in 1973 and these books...
Archiv fur Psychiatrie und Nervenkrankheiten
December 31, 1976
A Dittrich, P Bickel, J Schöpf et al.
8 citations
The study compares altered states of consciousness induced by the hallucinogens (--)delta9-trans-Tetrahydrocannabinol (delta9-THC) and N,N-Dimethyltryptamine (DMT) using two placebo control groups. A total of 24 subjects received 250 mug delta9-THC p.o./kg body weight and 26 subjects were treated with 250 mug DMT i.m./kg. Placebo was given to 24 subjects. The effects were assessed by a...
Pharmacology, Biochemistry, and Behavior
September 1976
F J Manning
Albino rats were given extensive training in spaced responding, using a DRL 30 sec schedule of food reinforcement (only lever presses more than 30 sec apart were reinforced). All rats then went 12 days without behavioral testing. During this period half the rats received daily intragastric doses of delta-9-tetrahydrocannabinol (THC) and the rest equal volumes of the THC vehicle. On day 13, some...
Psychopharmacologia
May 28, 1976
B A Peters, E G Lewis, R E Dustman et al.
Three dose levels, 0.2, 0.4, and 0.6 mg/kg, of delta9-tetrahydrocannabinol (THC) and a placebo were orally administered to 10 frequent and 10 occasional marijuana users. Following ingestion of each dose and the placebo, objective tests selected from a battery of sensory and perceptual motor tests routinely used to evaluate cerebral dysfunction in hospitalized patients were administered. The...
Psychopharmacologia
April 15, 1976
P G Waser, A Martin, L Heer-Carcano
The course of active avoidance learning of rats in a symmetrical Y-maze under the influence of 1, 3, and 9 mg/kg of delta 9-THC i.p., and 5, 20, and mug/kg of LSD was investigated. Delta-THC in a dosage of 1 mg/kg had no effect on avoidance learning. Three to a lesser extent 9 mg/kg produced more rapid learning with a significantly better performance. Learning under delta 9-THC proved to be...