Psychopharmacology
1984
B W Lex, J H Mendelson, S Bavli et al.
The effects of marijuana cigarette (1.8% THC) smoking on pulse rate and mood were studied under double-blind placebo-controlled conditions in 28 adult female volunteers during the follicular, luteal, and ovulatory phases of the menstrual cycle. Statistically significant increases in pulse rate, subjective levels of intoxication, and the POMS confusion factor occurred after marijuana smoking....
Psychopharmacology
1984
J H Mendelson, N K Mello
The reinforcing properties of delta 9THC (17.5 mg), a 1 g marijuana cigarette containing 1.83% delta 9-THC, a synthetic cannabis compound (Nabilone 2 mg orally), and their respective placebos were assessed with self-report and operant work-contingent choice procedures. Three groups of eight subjects were selected on the basis of a history of regular, intermittent, or occasional...
Fortschritte der Neurologie · Psychiatrie
July 1, 1983
K L Täschner
From 237 patients examined for drug-induced psychoses, 50 cannabis psychoses were examined according to the criterion "main cause of addiction" and 107 were examined according to the criterion "consumption during the last three months before hospitalization". The cannabis psychoses were compared to the other drug-induced psychoses as well as to a control group consisting of 219 schizophrenic...
The Lancet
December 18, 1982
D Rottanburg, A H Robins, O Ben-Arie et al.
The mental state of 20 psychotic men with high urinary cannabinoid levels on admission to a psychiatric hospital was compared with that of 20 matched cannabis-free controls. All patients underwent toxicological analysis to exclude the presence of alcohol and other exogenous agents. Cannabis levels were measured by a semiquantitative enzyme immunological technique and mental state was assessed...
Acta Psychiatrica Scandinavica
October 1, 1982
A Pålsson, S O Thulin, K Tunving
Eleven patients with a psychosis in connection with cannabis abuse admitted to two mental hospitals during 1 year were examined. Patients with a pre-existent psychosis or a mixed abuse were excluded. The patients were divided into three groups: acute, subacute and chronic. The features of the disease were essentially similar in all patients, with a mixture of affective and schizophrenia-like...
Psychopharmacology
1982
A W Zuardi, I Shirakawa, E Finkelfarb et al.
The object of the experiment was to verify whether cannabidiol (CBD) reduces the anxiety provoked by delta 9-THC in normal volunteers, and whether this effect occurs by a general block of the action of delta 9-THC or by a specific anxiolytic effect. Appropriate measurements and scales were utilized and the eight volunteers received, the following treatments in a double-blind procedure: 0.5...
Science
July 24, 1981
Jeffrey Schaeffer, Therese Andrysiak, J. Thomas Ungerleider
Neuropsychological variables and urine cannabinoid metabolites were evaluated in ten subjects born, raised, and educated in the United States and having histories of heavy or prolonged use of cannabis. No impairment of cognitive function was found. Cannabinoid metabolites in excess of 50 nanograms per milliliter were present in the ten urine samples. The tetrahydrocannabinol content of cannabis...
American Journal of Psychiatry
May 1981
D L Braff, L Silverton, D P Saccuzzo et al.
The authors conducted a double-blind crossover study to investigate the effects of marijuana on visual information processing. The authors used a tachistoscopic paradigm, and the results show no marijuana effect on the critical stimulus duration, a measure of stimulus intake. The visual backward masking data are compatible with a marijuana-induced slowness of information processing from labile...
Pharmacology, Biochemistry, and Behavior
June 1979
S E Rose, W O Dwyer, A L Yehle
The effect of Delta 9-tetrahydrocannabinol (THC) on the ability of rabbits to detect a minimal light stimulus (absolute visual threshold) was examined using the method of limits with an aversive classical conditioning paradigm. Both of two dosage levels of THC, similar to an amount ingested by a human from a single cigarette, significantly elevated the absolute visual threshold of all animals....
Psychopharmacology
March 22, 1979
P L Clopton, D S Janowsky, J M Clopton et al.
The influence of marijuana on the ability to perceive emotions in others was studied in 30 male volunteers who were experienced marijuana users. Subjects smoked either placebo or active marijuana containing 6 mg delta 9-THC. The Affective Sensitivity Scale, a test developed to measure the ability to perceive emotions in others, was divided at midpoint and the two halves were administered before...