Psychiatric Bulletin
November 1, 1988
Roland Littlewood
20 citations
Concern among black and ethnic minorities with current research in ‘transcultural psychiatry’ entails future work taking into account their collaboration to minimise the possibility that it is prejudicial to their interests. An instance is given of a project initiated by black community groups which looks at psychiatric conceptualisations of a diagnosis commonly used locally in inner-city...
Pharmacology, Biochemistry, and Behavior
November 1988
S J Heishman, M L Stitzer, G E Bigelow
This study compared subjective and performance dose effect profiles of oral alcohol and smoked marijuana. Male subjects (N = 6) with histories of moderate alcohol and marijuana use received three doses of alcohol (0, 0.6, 1.2 g/kg) and three doses of marijuana (0, 1.3, 2.7% delta 9-THC) in a double-blind, randomized crossover design. Physiological indices indicated that active drug was...
Psychopharmacology
1988
T G Aigner
The effects of orally administered delta-9-tetrahydrocannabinol (THC) were evaluated on two different learning abilities in monkeys. Visual recognition memory, known to depend on limbic system integrity, was tested by means of delayed nonmatching-to-sample and found to be significantly impaired by acute administration of 2 and 4 mg/kg THC given 1 or 2 h prior to testing. Performance was...
Psychopharmacology
1988
L D Chait, S M Evans, K A Grant et al.
The discriminative stimulus (DS) effects of smoked marijuana were studied by training marijuana smokers to discriminate between the effects of marijuana containing 2.7% delta 9-THC (M) and marijuana containing 0.0% delta 9-THC (P). In addition to measures of discrimination responding, subjective effects were assessed with standardized mood questionnaires. The post-smoking increase in expired...
Acta psychiatrica Scandinavica. Supplementum
1988
L E Hollister
In this updating review of research on cannabis particular attention has been paid to the increasing number of studies of the disposition of the components of cannabis in man, as well as possible effects on health. Specific binding sites for cannaboids have not been demonstrated. Approximately 80 metabolites of tetrahydrocannabiol (THC) have been discovered, of which 11-OH-THC is the main...
Psychopharmacology
1987
W D Hooker, R T Jones
The marijuana-induced acute memory impairment was assessed in a double-blind, crossover experiment. Twelve males smoked NIDA-supplied cigarettes containing 1.2% delta-9-tetrahydrocannabinol (THC) or cannabinoid-exhausted marijuana (placebo) in counterbalanced order on 2 days 1-3 weeks apart. Practice, pre- and postsmoking test sessions were conducted with the Paced Auditory Serial Addition...
Pharmacology, Biochemistry, and Behavior
September 1986
R Nemeth-Coslett, Jack E Henningfield, M K O'Keeffe et al.
Multiple measures of tobacco cigarette smoking and subjective and physiological effect were collected during 90 minute test sessions in volunteer cigarette smokers who also had histories of recreational marijuana use. Before sessions, subjects smoked one marijuana cigarette (placebo or 1.29%, 2.84%, 4.00%) using a standardized puffing procedure. Each dose and placebo was given four times to...
Pharmacology, Biochemistry, and Behavior
June 1986
E J Cone, R E Johnson, J D Moore et al.
Four healthy male subjects smoked two marijuana cigarettes or one marijuana cigarette and one placebo cigarette, or two placebo cigarettes on separate days in a random order crossover design. Each marijuana cigarette contained 2.8% delta-9-tetrahydrocannabinol (THC). Plasma hormones and THC were measured before and after each smoking session. Plasma LH was significantly depressed and cortisol...
International Journal of the Addictions
June 1986
R C Wert, M L Raulin
This paper examines the research evidence relating sustained use of marijuana to chronic cerebral impairment. Evidence from both American and cross-cultural studies is reviewed, with a particular emphasis on methodological problems in the research. The focus of this paper is on neurological findings while another paper focuses on neuropsychological findings. On the basis of available research,...
British Journal of Medical Psychology
June 1, 1986
C Moran
This paper examines the role of uncontrolled depersonalization associated with marijuana use in the development of agoraphobia. Cases of six people are described, all of whom reported first experiencing depersonalization while using marijuana, and subsequently experiencing depersonalization while not using the drug. A fear of this 'uncontrolled' depersonalization resulted in considerable...