European Psychiatry
April 1, 2017
F. Dumitrescu
Introduction: “Bath salts” target the endocannabinoid system in a similar manner to cannabis. In the case of designer drug misuse, subjects seem to be at higher risk of psychotic symptoms. Aims: To investigate the nature and frequency of psychotic symptoms associated with cannabis and/or bath salts misuse in a male inpatient population. Method: The files of 107 patients admitted to the...
European Psychiatry
April 1, 2017
M. Gomez Revuelta, María Juncal Ruiz, O. Porta Olivares et al.
Introduction The association between cannabis and psychosis makes crucial the intervention on cannabis use disorder at first episodes of psychosis (FEP), especially among young population. In this group of patients, the harmful potential of cannabis is more evident by its influence on neurodevelopment. However, the nature of the association cannabis-psychosis is not clearly described. It seems...
European Psychiatry
April 1, 2017
A. Oda
BackgroundWith the rapid and intensive spread of marihuana abuse among youth, Japanese society is focusing on law enforcement against drug abusers. In 2016, a mass killing allegedly committed by a marihuana abuser was reported in Japan.ObjectivesTo consider that common recognition of the diverse process and potential risks of cannabis psychosis should be shared among psychiatrists.AimsElicit...
March 28, 2017
A. Farah
The recent trend towards legalization and commercialization of marijuana in the US has resulted in a significant drop in the perceived risks of cannabis use among all age groups. Thus, legalization has further advances the common misperception that cannabis abuse and dependence are generally safe and devoid of neuropsychiatric sequelae. Yet there are numerous acute, as well as numerous...
Journal of Adolescent Health
March 17, 2017
Jason D. Jones, Monica E. Calkins, J. Scott et al.
Purpose To examine how cannabis use and polysubstance use among cannabis users relate to psychosis spectrum (PS) symptoms in a large community-based sample of US youth. Methods 4,171 youth (age 14–21; mean=16.90, SD=1.85; 55% female) from the Philadelphia Neurodevelopmental Cohort (PNC) completed assessments of substance use, PS symptoms, and confounding variables (e.g., demographics, comorbid...
Frontiers in Pharmacology
March 10, 2017
E. Brand, Zhong-Zhen Zhao
Cannabis sativa L. (Cannabaceae) has a long history of utilization as a fiber and seed crop in China, and its achenes (“seeds”) as well as other plant parts have been recorded in Chinese medical texts for nearly 2000 years. While the primary applications of cannabis in Chinese medicine center around the use of the achenes, ancient indications for the female inflorescence, and other plant parts...
Schizophrenia Bulletin
March 1, 2017
Robin Murray
Overall Abstract: Dr Marta Di Forti Cannabis use across Europe and its interaction with the polygenic risk score for schizophrenia. Dr Di Forti examined the pattern of cannabis use across 16 European sites as part of the EU-GEI study. She will show striking differences in incidence of psychosis (high in North and low in South), and how differences in pattern of cannabis use result in...
Cannabinoids and the Brain
March 1, 2017
Linda A. Parker
Although cannabis has been used throughout human history, the scientific investigation of its effects only began with the isolation of THC in the 1960’s. Once discovered it was another 20 years before the mechanism by which THC produces its psychoactive effects in the brain, the CB1 receptor, was discovered. Cannabis contains over 80 cannabinoid compounds, but THC is the only intoxicating...
Drug and Alcohol Dependence
March 1, 2017
Jenny L Wiley, Timothy W Lefever, Julie A. Marusich et al.
Women report greater sensitivity to the subjective effects of Δ9-tetrahydrocannabinol (THC). Similarly, female rodents tend to be more sensitive to some pharmacological effects of THC and synthetic cannabinoids. This study examined sex differences in discriminative stimulus and response rate effects of THC and synthetic cannabinoids in rats. A cumulative dosing THC discrimination procedure was...
Journal of the American Academy of Child & Adolescent Psychiatry
March 2017
Amir Levine, Kelly Clemenza, Moira A Rynn et al.
This review of the scientific literature examines the potential adult sequelae of exposure to cannabis and related synthetic cannabinoids in adolescence. We examine the four neuropsychiatric outcomes that are likely most vulnerable to alteration by early cannabinoid use, as identified within both the clinical and preclinical research: cognition, emotional functioning, risk for psychosis, and...