Drug and Alcohol Dependence
August 1, 2017
Emma Childs, Joseph A Lutz, Harriet de Wit
Cannabis smokers often report that they use the drug to relax or to relieve emotional stress. However, few clinical studies have shown evidence of the stress-relieving effects of cannabis or cannabinoid agonists. In this study, we sought to assess the influence of delta-9-tetrahydrocannabinol (THC), a main active ingredient of cannabis, upon emotional responses to an acute psychosocial stressor...
Addiction
July 31, 2017
Christine L. Miller
2 citations
The review of cannabis-induced psychosis by Ian Hamilton in Addiction 1 raised key issues that warrant further exploration. In focusing upon the literature up to the turn of the 21st century, the author omitted the subsequent explosion of scientific inquiry into a causal relationship between cannabis use and chronic psychotic disorders. The author pointed towards one type of relevant research,...
Addiction
July 31, 2017
Ian Hamilton
The points made by Dr Miller 1 raise further important issues we need to consider in thinking about the relationship between cannabis and psychosis. With regard to later research, I accept that much of the research published after the millennium was not included in my original paper, as the focus was upon how work prior to this time had evolved and how well it had stood the test of time. The...
Addiction
July 22, 2017
Madeline H. Meier, Avshalom Caspi, Andrea Danese et al.
129 citations
AIMS: This study tested whether adolescents who used cannabis or met criteria for cannabis dependence showed neuropsychological impairment prior to cannabis initiation and neuropsychological decline from before to after cannabis initiation. DESIGN: A longitudinal co-twin control study. SETTING AND PARTICIPANTS: Participants were 1989 twins from the Environmental Risk (E-Risk) Longitudinal Twin...
Drugs and Alcohol Today
July 20, 2017
Mark E. Shevlin, Eoin McElroy, Jamie Murphy et al.
8 citations
Purpose While research has consistently identified an association between cannabis use and psychosis, few studies have examined this relationship in a polydrug context (i.e. combining cannabis with other illicit substances). The paper aims to discuss this issue. Design/methodology/approach The present study sought to examine the association between recreational drug use (cannabis only vs...
Annals of General Psychiatry
July 12, 2017
Ahmed Mhalla, Bochra Ben Mohamed, Christoph Ulrich Correll et al.
8 citations
Neurological soft signs (NSS) are minor non-localizing neurological abnormalities that are conceptualized as neurodevelopmental markers that mediate the biological risk for psychosis. We aimed to explore the relationship between NSS and cannabis use, an environmental risk factor of psychosis. This was a cross-sectional study in consecutively admitted patients hospitalized for first-episode...
The Lancet Psychiatry
July 10, 2017
Tabea Schoeler, Natalia Petros, Marta Di Forti et al.
142 citations
Background Cannabis use following the onset of first-episode psychosis has been linked to both increased risk of relapse and non-adherence with antipsychotic medication. Whether poor outcome associated with cannabis use is mediated through an adverse effect of cannabis on medication adherence is unclear. Methods In a prospective analysis of data acquired from four different adult inpatient and...
Drug and Alcohol Dependence
July 8, 2017
Sandra Thijssen, B. Rashid, Shruti Gopal et al.
Cannabis and alcohol are believed to have widespread effects on the brain. Although adolescents are at increased risk for substance use, the adolescent brain may also be particularly vulnerable to the effects of drug exposure due to its rapid maturation. Here, we examined the association between cannabis and alcohol use duration and resting-state functional connectivity in a large sample of...
Psychopharmacology
July 2017
Erin M Rock, Cheryl L Limebeer, Gavin N Petrie et al.
Cannabis is commonly used by humans to relieve stress. Here, we evaluate the potential of intraperitoneally (i.p.) administered Δ9-tetrahydrocannabiol (THC) and cannabidiolic acid (CBDA, the precursor of cannabidiol [CBD]) to produce dose-dependent effects on anxiety-like responding in the light-dark (LD) emergence test of anxiety-like responding in rats, when administered acutely or...
Cultura y Droga
July 1, 2017
Nidia Hernández, José Domingo Schievenini Stefanoni
2 citations
Objetivo. Analizar las posibles denominaciones indígenas del cannabis durante el período novohispano, así como las probables continuidades de esta concepción durante el siglo XIX. Metodología. Se revisaron fuentes documentales y etnográficas que sugieren que la denominación indígena del cannabis se relacionó con el término pipiltzintzintli, cuya concepción transitó ―de manera subrepticia― de un...