Psychology and sexuality
2018
Joseph J Palamar, Marybec Griffin-Tomas, Patricia Acosta et al.
Alcohol, marijuana, and ecstasy (3,4-methylenedioxymethamphetamine [MDMA], 'Molly') are among the most prevalent substances used by young adults; however, few studies have focused on the specific sexual effects associated with use. Examining subjective sexual effects (e.g. increased libido) associated with use can inform prevention efforts. Data were analysed from 679 nightclub and dance...
The American Journal of Drug and Alcohol Abuse
2018
Melanie Rylander, Helena R Winston, Haley Medlin et al.
The associations between cannabis use and psychosis are well documented in numerous studies. There is a need to evaluate the impact of cannabis use on inpatient psychiatric utilization and outcomes. To evaluate the impact of cannabis use on psychiatric hospital outcomes. This study was conducted between April 20, 2015 and October 20, 2015. All patients (n = 120) admitted to Denver Health with...
Salud Mental
December 12, 2017
Carlos Roncero, Servicio de Psiquiatría Complejo Asistencial Universitario de Salamanca (causa) Instituto de Biomedicina de Salamanca (ibsal) Universidad de Salamanca Salamanca España., Raul Felipe Palma-álvarez et al.
11 citations
Background. Cannabis is the most widely used illegal drug in the world. Both an early cannabis use onset and the amount used contribute to the risk of suffering mental disorders in adulthood. Objective. Review longitudinal studies conducted on adolescents associating early cannabis use with the subsequent occurrence of mental disorders. Method. A search was conducted in PubMed until December...
European Journal of Clinical Pharmacology
December 2017
Carmen Walter, Bruno G Oertel, Lisa Felden et al.
Considering the increasing acknowledgment of the human sense of smell as a significant component of the quality of life, olfactory drug effects gain potential clinical importance. A recent observation in a human experimental context indicated that Δ9-tetrahydrocannabinol (THC) impaired the subject's performance in olfactory tests. To further analyze the role of THC in human olfaction, the...
Drug and Alcohol Dependence
December 1, 2017
Amy T Nusbaum, Paul Whitney, Carrie Cuttler et al.
Cannabis use has increased rapidly in recent decades. The increase in cannabis use makes it important to understand the potential influence of chronic use on attentional control and other executive functions (EFs). Because cannabis is often used to reduce stress, and because stress can constrain attentional control and EFs, the primary goal of this study was to determine the joint effect of...
Pharmacology, Biochemistry, and Behavior
December 2017
C R Kasten, Y Zhang, S L Boehm
Use of exogenous cannabinoids disrupts the fine-tuned endocannabinoid receptor system, possibly leading to alterations in cognition, memory, and emotional processes that endure long after cannabinoid use has stopped. Long-term adolescent use may uniquely disrupt these behaviors when compared to adult use. The current study explored the acute and long-term behavioral effects of six 10mg/kg...
European Neuropsychopharmacology
December 2017
Tomáš Hložek, Libor Uttl, Lukáš Kadeřábek et al.
Metabolic and behavioural effects of, and interactions between Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are influenced by dose and administration route. Therefore we investigated, in Wistar rats, effects of pulmonary, oral and subcutaneous (sc.) THC, CBD and THC+CBD. Concentrations of THC, its metabolites 11-OH-THC and THC-COOH, and CBD in serum and brain were determined over 24h,...
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
November 23, 2017
Peter Manza, Dardo G. Tomasi, Nora D. Volkow
61 citations
BACKGROUND: Cannabis abuse (CA) has been associated with psychopathology, including negative emotionality and higher risk of psychosis, particularly with early age of initiation. However, the mechanisms underlying this association are poorly understood. Because aberrant dopamine signaling is implicated in cannabis-associated psychopathology, we hypothesized that regular CA would be associated...
CRC Press eBooks
November 22, 2017
Richard Bryant‐Jefferies
Charlotte is working with Ali, who is in his late teens. He is the son of Fareeda. His father is white, English and he has a younger brother, Adam. Her supervisor is Matt. Ali has been using cannabis for some years, and has begun using the stronger ‘skunk’ cannabis which is more powerful than the dope, grass and marihuana of previous years. It is difficult to know whether his cannabis use...
PLoS One
November 11, 2017
Ana González-Pinto, Itxaso González-Ortega, Susana Alberich et al.
The objective of this study is to investigate cognitive performance in a first-episode psychosis sample, when stratifying the interaction by cannabis use and familial or non-familial psychosis. Hierarchical-regression models were used to analyse this association in a sample of 268 first-episode psychosis patients and 237 controls. We found that cannabis use was associated with worse working...