Progress in Neuro-Psychopharmacology and Biological Psychiatry
January 10, 2021
Hanna J Szkudlarek, Mar Rodríguez-ruiz, Roger Hudson et al.
Clinical and pre-clinical evidence demonstrates divergent psychotropic effects of THC vs. CBD. While THC can induce perceptual distortions and anxiogenic effects, CBD displays antipsychotic and anxiolytic properties. A key brain region responsible for regulation of cognition and affect, the medial prefrontal cortex (PFC), is strongly modulated by cannabinoids, suggesting that these dissociable...
Schizophrenia Research
January 9, 2021
Leah G. Pope, M. Manseau, M. Kelley et al.
OBJECTIVE The nature of associations between recent cannabis use and negative symptoms, positive symptoms, and neurocognitive deficits remains unclear. In a relatively large sample of well-characterized patients with first-episode psychosis, we hypothesized that, compared to first-episode patients without cannabis use in the three months prior to first hospitalization, those having used...
Journal of Psychopharmacology
January 9, 2021
Abigail M. Freeman, Claire Mokrysz, Chandni Hindocha et al.
6 citations
BACKGROUND: While the acute effects of cannabis are relatively benign for most users, some individuals experience significant adverse effects. This study aimed to identify whether variation in schizotypal personality traits and frequency of cannabis use influence the acute effects of delta-9-tetrahydrocannabinol (THC). METHODS: Individual participant data from four double-blind, randomised,...
Libro Comunicaciones
2021
4-bromo-2,5-dimetoxifeniletilamina, también conocido como 2C-B, "tussi", "nexus" o "cocaína rosa" es una droga sintética del grupo de las feniletilaminas, con efectos alucinógenos y euforizantes, debido a su efecto como agoniza parcial de receptores 5HT-2A, 5HT-2B y 5HT-2C, cuyo consumo se ha extendido en los últimos años. Presentamos el caso de una paciente de 22 años sin antecedentes...
Libro Comunicaciones
2021
Maitane Oscoz-Irurozqui, Maria Guardiola-Ripoll, Carmen Almodóvar-Payá et al.
1. Objectives: While endocannabinoid system seems to be involved in processes underlying psychosis, research about Cannabinoid Receptor 2 gene (CNR2) is scarce and inconclusive. Some few reports indicate that CNR2 plays a role in psychiatric conditions, including depression or drug addiction (Onaivi et al., 2009). We aimed to evaluate the role of CNR2 and its interplay with cannabis on...
Frontiers in Neuroscience
2021
Christian D Richard, Jared R Poole, Marissa McConnell et al.
The trend toward cannabis legalization in the United States over the past two decades has unsurprisingly been accompanied by an increase in the number of cannabis users and use patterns that potentially pose wider risks to the public like driving under the influence. As such, it is becoming increasingly important to develop methods to accurately quantify cannabis intoxication and its associated...
Brazilian Journal of Health Review
2021
Marina Bertoldo Baeza, Ricardo S. S. Durães, Antonio de Pádua Serafim
Background: Studies have pointed out the increased risk of developing psychosis in adulthood related to cannabis use during adolescence.Aim: To conduct a systematic review of the literature on the use of cannabis in adolescence and risk of psychosis.Method: We conducted a systematic review in accordance with PRISMA guidelines.We searched by PubMed, PsycINFO, and SciELO database between 2010 and...
Archives of Clinical and Medical Case Reports
2021
Zoe Boulot, F. Gabayet, Mathieu Besnard et al.
We describe a young male patient who questions his diagnosis of schizophrenia made 10 years ago, and whose clinical presentation and history seem in favour of cannabisinduced psychotic episodes. This case questions the risk of a hasty diagnosis when it comes to concomitant psychosis and cannabis use. This presentation raises medical, therapeutical, and ethical questions. With cannabis use...
Turk psikiyatri dergisi = Turkish journal of psychiatry
2021
U. Kırlı, T. Binbay, K. Alptekin et al.
OBJECTIVE The aim of this study is to evaluate the associations between alcohol-cannabis use and forensic/stressful events with the risk of incident clinical psychosis during follow-up. METHOD A community-based sample (n: 2142) was screened for clinical psychosis (schizophrenia and other psychotic disorders, affective disorders with psychotic features) at baseline and follow-up. Thus, incident...
Traffic injury prevention
2021
Thomas S Burt, Timothy L Brown, Rose Schmitt et al.
Reports indicate that cannabis users will adapt their driving to compensate for the perceived drug effects of cannabis. This analysis examined the relationship between driver perceptions of their state contrasted with objective measures of their performance while operating a motor vehicle. Data was collected from ten subjects in a study examining the effects of cannabis on driving performance....
Medicina
2021
A. J. Kolgashkin, П. Н. Николаев, E. J. Tetenova et al.
1 citation
Cannabis continues to be the most widely used drug worldwide. Recently, there has been two trends in the field: a liberalization of cannabis-related legislation in a number of countries, as well as an increase in the content of the psychoactive component in cannabis plant – tetrahydrocannabinol. The review covers a topic that has been little studied in Russian addiction science – cannabis use...
2021
Natasha Leigh Mason
Cannabis is the most commonly used illicit drug and is known to alter state of consciousness and impair neurocognitive function. However, the mechanisms underlying these effects have yet to be fully elucidated. Rodent studies suggest that 9-tetrahydrocannabinol (THC) activates dopaminergic neurons in the limbic system, subsequently enhancing dopamine, which is implicated in the rewarding...