Dangerous Harvest
April 22, 2004
James H. Mills
When approaching the subject of rural producers and their environments in nineteenth-century India, it is necessary to be mindful of the range of studies during the last 30 years or so that have emphasised the importance of resistance to colonial projects. These studies, most notably those published in the Subaltern Studies project (Guha 1982), have focused on the strategies and agendas of...
Addiction
March 25, 2004
Zerrin Atakan
2 citations
Sir—Does cannabis use cause a psychotic illness? About 150 years ago this question was already being asked, particularly recognizing the risk of ‘madness’ among young people, while at the same time the practice of using cannabis as a ‘medicine for insanity’ was being carried out in asylums (Mills 2003). It is interesting that over a century later the same question still remains unanswered,...
Molecular and cellular neurosciences
March 2004
Tiziana Rubino, Greta Forlani, Daniela Viganò et al.
Acute Delta(9)-tetrahydrocannabinol (THC) injection increased ERK pathway (ERK, pCREB, and c-fos) mostly in the caudate putamen and cerebellum. This effect underwent to homeostatic adaptation after chronic treatment. Moreover, chronic THC exposure induced increases in the ERK cascade (ERK, pCREB, and Fos B) in the prefrontal cortex and hippocampus, suggesting that different neuronal circuits...
Neuropsychopharmacology
March 2004
Christopher D. Verrico, J David Jentsch, Robert H Roth et al.
The residual neuropsychological effects of marijuana abuse in man indicate a dysfunction of the attentional/executive systems. Moreover, experimental investigations suggest that repeated, intermittent (subchronic) Delta(9)-tetrahydrocannabinol (THC), the main psychoactive ingredient of marijuana, alters neurotransmission in the frontal cortex of rats and humans, a key neural site mediating...
Journal of Nepal Medical Association
March 1, 2004
Kapil Dev Upadhyaya
2 citations
Panic disorder was seen as the most common presentation amongst the cannabis users who presented in thepsychiatric out patients of Western regional hospital for the treatment.Key Words: Panic disorder, Cannabis.
The British Journal of Psychiatry
January 30, 2004
Louise Arseneault, Mary Cannon, John Witton et al.
924 citations
BACKGROUND: Controversy remains as to whether cannabis acts as a causal risk factor for schizophrenia or other functional psychotic illnesses. AIMS: To examine critically the evidence that cannabis causes psychosis using established criteria of causality. METHOD: We identified five studies that included a well-defined sample drawn from population-based registers or cohorts and used prospective...
Journal of Pharmacological Sciences
2004
Hiroshi Ujike, Yukitaka Morita
94 citations
Cannabis consumption may induce psychotic states in normal individuals, worsen psychotic symptoms of schizophrenic patients, and may facilitate precipitation of schizophrenia in vulnerable individuals. Recent studies provide additional biological and genetic evidence for the cannabinoid hypothesis of schizophrenia. Examinations using [3H]CP-55940 or [3H]SR141716A revealed that the density of...