Aracê.
September 29, 2026
Renato Lemes Peixoto, Lígia Freitas
A Ayahuasca é uma preparação de origem amazônica tradicionalmente produzida a partir da combinação de Banisteriopsis caapi e Psychotria viridis, contendo compostos biologicamente ativos como N,N-dimetiltriptamina (DMT), harmina, harmalina e tetrahidroharmina. Nas últimas décadas, sua utilização ultrapassou os contextos tradicionais e religiosos amazônicos, alcançando centros urbanos e...
Industrial Psychiatry Journal
September 25, 2026
Julio Torales, Marcelo O’Higgins, Iván Barrios et al.
ABSTRACT: Ayahuasca, a traditional Amazonian brew containing N,N-dimethyltryptamine (DMT) and β-carboline monoamine oxidase inhibitors, has expanded globally beyond Indigenous ceremonial systems. While acute visionary and psychotomimetic effects are expected and culturally integrated in ritual contexts, concerns have emerged about persistent psychotic symptoms in vulnerable individuals. This...
Journal of Ethnopharmacology
September 24, 2026
Yurani Carolina Saavedra-Saenz, Marcelo Simas E Silva, Omar Enrique Estrada Semprun et al.
Ayahuasca is an entheogenic beverage traditionally used by Indigenous peoples and local communities throughout Amazonia. Its preparation typically involves the vine Banisteriopsis caapi and the leaves of Psychotria viridis, widely recognized as its principal ingredients. Other plant species and ethnotaxa have also been historically reported in association with ayahuasca preparation, but their...
Psychoanalytic Inquiry
September 22, 2026
Rodolfo Olivieri, Christine Avedikian, Mário Eduardo Costa Pereira et al.
Ayahuasca users often report receiving “messages” or a silent “voice” experienced as coming from an external instance that is neither the self nor other humans present. Building on Diament, Gomes, and Tófoli’s notion of a “plant third party,” we rename this phenomenon the plant third to foreground the field in which alterity is encountered. We first read the plant third through Lacanian...
Journal of Neural Transmission
September 19, 2026
Guilherme Lodetti, Henrique Redivo, Amanda Gomes Teixeira et al.
Pharmacotherapy for depression is commonly prescribed, yet fewer than half of patients achieve remission with a single treatment. Many also experience intolerable side effects, highlighting the need for new treatment approaches. Classic psychedelics interact with the serotonin (5-HT) receptor class and are therefore strongly involved in the treatment of psychiatric illnesses such as depression,...
Journal of Clinical Psychopharmacology
September 18, 2026
Renan Massanobu Maekawa, Lorena T. L. Guerra, Bianca Villanova et al.
Background: Depressive and anxiety symptoms are highly prevalent among patients with cancer and are associated with substantial reductions in quality of life. However, effective therapeutic options remain limited. Ayahuasca, a serotonergic psychedelic traditionally used in Amazonian ritual contexts, has shown rapid antidepressant and anxiolytic effects following a single administration in...
Frontiers in Psychiatry
September 15, 2026
Serena Chiara Civardi, Filippo Besana, Federico Durbano et al.
Background Treatment-resistant depression (TRD) is a major clinical challenge, with many patients failing to respond to conventional antidepressants. Psychedelic compounds such as psilocybin and ayahuasca have recently gained attention as potential rapid-acting therapies. Beyond their neurobiological effects, methodological, ethical, and real-world applicability concerns are critical for...
npj Mental Health Research
September 10, 2026
Lucas Cruz, Marcio S. C. Longo, Rafael S. Rodrigues et al.
Abstract This observational survey study investigated the relationship between prior ayahuasca experience and mental health and mindset outcomes. Participants planning to attend an ayahuasca ceremony completed a survey before their upcoming ayahuasca use. Measures included substance use, depression, anxiety, stress, spiritual well-being, aberrant salience, and metaphysical beliefs. Participants...
Anales de la Facultad de Medicina
September 9, 2026
Kary Gonzales Dávila, Yolanda Angulo-Bazán, Giancarlo Biaggi Ortega et al.
Introducción: La ayahuasca (también llamada huasca, oasca, caapi o yagé) es un brebaje de uso tradicional, con efectos psicoactivos de interés en la salud humana. Esta situación crea la necesidad de generar conocimiento científico para identificar vacíos en el conocimiento y prioridades en investigación. Objetivo. Describir la producción científica sobre el uso de ayahuasca en seres humanos...
International Journal of Science and Research (IJSR)
September 1, 2026
Raluca BilacoRusu
Empirical and philosophical interest in psychedelic substances has expanded substantially in recent years, extending beyond clinical applications to questions concerning altered states of consciousness and their possible effects on beliefs about reality. This paper reviews recent empirical research on psychedelic-associated changes in metaphysical belief, focusing on the prospective survey...