PsychedelicsMay 16, 2026Nádia Valéria Moreira Santos, Cristiane Ferreira Silveira, Camila Gutieres Dos Santos Soares Costa et al.
Aim This study aimed to explore the experiences and perceived effects of ayahuasca ceremonies on suicidality. Method We conducted in-depth qualitative interviews with nine participants from the North and Southeast regions of Brazil. These participants were part of a larger cohort and were selected to explore their perspectives on how ceremonial experiences with ayahuasca in neoshamanic contexts...
Parkinson's disease is a progressive neurodegenerative disorder with increasing global prevalence, primarily driven by population ageing. A hallmark of the disease is the degeneration of nigrostriatal dopaminergic neurons, accompanied by marked activation of glial cells and a sustained neuroinflammatory response. Current pharmacological treatments are limited to symptomatic relief and do not...
Parkinson's disease is a progressive neurodegenerative disorder with increasing global prevalence, primarily driven by population ageing. A hallmark of the disease is the degeneration of nigrostriatal dopaminergic neurons, accompanied by marked activation of glial cells and a sustained neuroinflammatory response. Current pharmacological treatments are limited to symptomatic relief and do not...
Background and Purpose: Ayahuasca can produce a dynamic set of both positive and negative acute effects. Commonly reported challenges include physical symptoms (e.g., nausea, vomiting) and emotional distress (e.g., frightening hallucinations, paranoia). Despite these difficulties, many individuals describe their challenging experiences as contributing to personal healing and beneficial...
CIENCIAMATRIAMay 1, 2026Azul Monserrathe Illicachi-Erazo, David Alejandro Toapanta-Amores
El objetivo general de la investigación fue analizar el uso Inadecuado de la ayahuasca y sus impactos en la salud. La investigación utilizó el método cuantitativo el cual produjo datos descriptivos, que se originaron por la recolección de datos. Se apoyó en la revisión documental-bibliográfica. Además, se empleó el método inductivo-deductivo. Se planteó además el método analítico-sintético....
OBJECTIVE: 'Ego dissolution' refers to a temporary state characterized by diminished self-referential processing, which leads to a breakdown of personal boundaries and an enhanced sense of unity with the environment. Both psychedelics, such as ayahuasca, and contemplative practices, like meditation, have been proposed as mechanisms for modulating the ego. While ayahuasca induces transient...
Abstract Introduction Ayahuasca is a psychoactive brew used in Amazonian ceremonies, containing monoamine oxidase inhibitors (MAOIs) from Banisteriopsis caapi and N,N-dimethyltryptamine (DMT) from Psychotria viridis or Diplopterys cabrerana. Its global use has expanded for perceived antidepressant and anti-addictive effects. However, its MAOI content predisposes users to serotonergic toxicity...
Novum JusApril 29, 2026Francisco Javier Esteban Guinea
En nuestra investigación comenzaremos por definir qué es la ayahuasca, cuáles son sus efectos y qué riesgos produce su consumo para la salud pública. El empleo de la ayahuasca en rituales chamánicos, religiosos, psicoterapéuticos o de autoconocimiento se ha expandido en los últimos decenios por casi todo el planeta. Los diversos usos del brebaje psicoactivo plantean retos a los diferentes...
Journal of Psychoactive DrugsApril 23, 2026Brayan Jonas Mano-Sousa, Maria Clara Gama Fontes, Ana Clara Anacleto Gonçalves et al.
Suicide, particularly in treatment-resistant depression (TRD), remains a pressing global health issue, with over 700,000 annual deaths. Existing treatments often have limited efficacy and delayed onset, creating a need for rapid-acting interventions. Ayahuasca, a traditional Amazonian psychedelic, has shown potential for rapidly reducing suicidal ideation. Our systematic review evaluated the...