Archives of General Psychiatry
November 1, 1967
William H. Mcglothlin
118 citations
THIS IS A report of a study designed to measure personality, attitude, value, interest, and performance changes resulting from the administration of LSD to normals. Several investigators using LSD with humans in nontherapy experiments have observed that some of their subjects report various lasting effects attributable to the drug experience. 1,2 In addition, the recent controversy over the...
JAMA
September 11, 1967
Doris H. Milman
18 citations
A 5-year-old girl with an apparently normal premorbid personality and adjustment became acutely psychotic following a single accidental ingestion of 100μg of d-lysergic acid diethylamide (LSD), with agitation, panic, depression and flattening of affect, disorientation, feelings of depersonalization, distortion of body image, and depression of intellectual functioning. In addition she displayed...
Canadian Psychiatric Association Journal
April 1, 1967
Peter Brawley, Robert Pos
5 citations
To summarize briefly: Converging data from many disciplines — psychology, psychiatry, social theory, biochemistry, neuropharmacology, neurophysiology — point to the sensory input regulating mechanism of the central nervous system as a critical factor in the production of hallucinoses and psychotic experience. There is good evidence that what we have called the informational underload model...
Journal of Asthma Research
1965
Harold A. Abramson, Anabela P. Rolo
21 citations
This paper is a continuation of our experiments with LSD-25 and similar compounds that have been carried out for the last thirteen years.1 It employs the same technique described previously2 to compare these drugs on non-psychotic test subjects under suitable conditions. The conditions of the experiment are most important because under certain circumstances the experimental milieu produces so...
Nature
1964
N. J. Giarman
This Special Issue of Neuropharmacology on psychedelics provides a timely and comprehensive update on progress following the previous Neuropharmacology Special Issue “ Psychedelics: New Doors, Altered Perceptions ” . Remarkable advances have been made in basic and clinical research on psychedelics in the five years since 2018. It is partly based on the seminar series focused on psilocybin...
Quarterly Journal of Experimental Psychology
June 1, 1955
Roger W. Russell, Hannah Steinberg
It has been demonstrated that exposure to the stress of a situation involving conflict or frustration may interfere significantly with subsequent learning. Behaviour under stress is characterized by experiences of “anxiety” and by widespread physiological changes. Inhalation of nitrous oxide has the general effect of reducing the extent of these symptoms. The present investigation using...
American Journal of Psychiatry
February 1, 1948
J. Louise Despert
43 citations
The records of three groups of children—normal, preschool children; children with behavior and neurotic problems; and finally, psychotic children—were analyzed with a view of gaining information about and insight into hallucinatory and delusional phenomena in children. The large majority of the children belonged in the normal and superior range of intellectual functioning. No evidence of true...
Journal of Mental Science
1947
G. Tayleur Stockings
Depersonalization, or feeling of unreality, is a symptom which may occur as part of several psychiatric conditions, such as hysteria, anxiety and obsessional states, and some forms of schizophrenia and endogenous depression. The true derealization-depersonalization syndrome, however, in which the unreality symptom is the primary disturbance, is a quite peculiar and distinctive condition, which...
Home healthcare now
Jala Sireesha, Jayasree Manukinda, Sudhindra Vooturi et al.
Progressive functional decline and behavioral disturbances in people with dementia place sustained emotional and practical demands on family caregivers, often resulting in chronic stress, anxiety, depression, and a high perceived caregiving burden. This pilot study examined the effects of an 8-week online Mindfulness-Based Stress Reduction (MBSR) program on psychological burden and well-being...
Clinical Neuropharmacology
Megan Jayne Ralston, Alim Osman
1 citation
This study reviews literature on the psychiatric effects of delta-8-THC, particularly psychosis and severe mental health outcomes, to highlight the need for further research and regulation. Marijuana, the most widely used illicit drug in the United States, sees increasing use due to legalization. Although moderate use is generally safe, adverse effects can occur, especially in those with...