There is controversy about a causal role of serotonin (5-HT) in depression, some arguing that there is no proof for impaired brain 5-HT function in depressed patients. Major depressive disorder comes with multiple endophenotypes; not surprisingly classical antidepressants (tricyclics, MAO inhibitors, SSRIs, SNRIs) are not universally effective. Most antidepressants target the 5-HT system,...
Symptoms of anxiety and depression are common in patients with terminal illness and multiple challenges exist with timely and effective care in this population. Several centres have reported that one dose of the serotonergic psychedelic psilocybin, combined with therapeutic support, improves these symptoms for up to 6 months in this patient group. Drawing upon related therapeutic mechanisms,...
Numerous studies have revealed an alarming prevalence of test anxiety among Chinese junior high school students. Prevention of test anxiety in this population has become crucial. Brief meditation intervention (BMI) has shown promising results for promoting students’ well-being and reducing test anxiety, but its mechanism for reducing test anxiety remains unknown. This study examined the effects...
Mental health research is often focused on alleviating psychological distress rather than increasing well-being. This study approached mental health from a dual-continua model (DCM) framework, which allows for distress and well-being to co-occur. The aims of the present study were to expand upon DCM literature by examining differences in psychological well-being indicators among a broad adult...
Generalized anxiety disorder is a type of anxiety disorder that is defined as excessive and unreasonable worry about everyday events and activities. The present study was conducted with the aim of determining the effectiveness of positive mindfulness therapy on the affective capital and metaemotions of women with generalized anxiety disorder in Isfahan, Iran. The research method was a...
The purpose of this study was to compare the effectiveness of a mindfulness-based cognitive intervention and a metacognitive intervention on anxiety symptoms and rumination in patients with multiple sclerosis. The method of this study was based on the purpose and research design and was quasi-experimental and pretest-posttest with a control group. For this purpose, among all women with MS under...
The aim of this study was to examine the effectiveness of a mindfulness-based group stress reduction training on premenstrual symptoms and anxiety in women. This study was a practical and quasi-experimental design with pretest-posttest follow-up and a control group. The statistical population of this study included all female students of Islamic Azad University, Karaj Branch in 2017, of which...
The Indian pharmaceutical industry is one of the fastest-growing sectors of the Indian economy and ranks among the top 15 drug-manufacturing countries globally. Among the fastest-growing industries in the world, the pharmaceutical industry has increased over the years. A pharmaceutical company appoints a medical representative to make their products easily reach healthcare specialists and then...
The study investigated the effects of loving-kindness meditation (LKM) on doctors' communication anxiety, trust, calling, and defensive medicine practice. This study recruited 94 doctors from a hospital in China, randomized them to an LKM group (n = 47), and waited for the control group (n = 47). The experimental group accepted an 8-week LKM interference while the waiting for the control group...
Background: Theories propose that judgment of and reactivity to inner experiences are mediators of the effect of mindfulness-based interventions on generalized anxiety disorder (GAD). However, no study has tested such theories using brief, mindfulness ecological momentary intervention (MEMI). We thus tested these theories using a 14-day MEMI versus self-monitoring app (SM) control for GAD....