Background: Psilocybin is a serotonergic psychedelic found in “magic mushrooms” with a putative therapeutic potential for treatment-resistant depression, anxiety, obsessive-compulsive disorder, and addiction. In rodents, psilocybin acutely induces plasticity-related immediate early genes in cortical tissue; however, studies into the effects on subcortical regions, of different doses, and the...
Objectives: To examine relationships in mindfulness and illness acceptance and psychosocial functioning in patients with metastatic breast cancer and their family caregivers. Sample & setting: 33 dyads from an academic cancer center in the United States. Methods & variables: Participants completed questionnaires on mindfulness, illness acceptance, relationship quality, anxiety, and depressive...
The art of meditation has attracted vivid attention and considerable interest in contemporary unstable and unpredicted world, especially now when the outbreak of COVID-19 has created mental health concerns among the general population worldwide. Contemporary research on meditation for different conditions shows that meditation helps to control pain, may reduce blood pressure, leads to increases...
Much of the burden associated with poor mental health is associated with symptom experience in the general population. We conducted a systematic review and meta-analysis of studies conducted in non-clinical samples, evaluating Mindfulness-Based Programs (MBPs) for outcomes related to psychological health and well-being. We focussed on Mindfulness-Based Stress Reduction (MBSR) and...
More than 100 years of retrospective studies show that psychosis is usually preceded by a prodrome. Nonspecific symptoms such as anxiety and depression precede more specific negative and attenuated positive symptoms. Prospective diagnostic criteria have been developed based on the retrospective work. The prospective criteria have shown high reliability in the research context, and follow-up...
Remaja, terutama remaja akhir yang mengalami fase transisi ke dewasa awal dan masuk ke perguruan tinggi rentan mengalami kecemasan karena perubahan-perubahan yang terjadi dalam waktu yang cukup singkat. Tingkat kecemasan yang tinggi pada mahasiswa baru berpotensi menurunkan performa akademik dan jika tidak segera ditangani dapat menyebabkan masalah yang lebih serius. Penelitian ini bertujuan...
BACKGROUND AND PURPOSE Little data is available on the effect of mindfulness amongst pediatric hematology-oncology professionals. The purpose was to further document change in biological and psychological stress following a mindfulness-based stress reduction (MBSR) program. MATERIALS AND METHODS We led two pre-post interventional studies (n = 12 and n = 25) and measured changes on hair cortisol...
Abstract Objective Preliminary findings suggest that different kinds of meditation could work on diverse cognitive and psychological processes. The present study aimed at disentangling the effects of three mindfulness techniques on mental rumination and subjective time perspective. Design: 75 young healthy participants were randomly assigned to one of four conditions: mindful breathing, body...
Abstract Growing interest has been seen in using lysergic acid diethylamide (LSD) in psychiatric research and therapy. However, no modern studies have evaluated subjective and autonomic effects of different and pharmaceutically well-defined doses of LSD. We used a double-blind, randomized, placebo-controlled, crossover design in 16 healthy subjects (eight women, eight men) who underwent six 25...
Mindfulness-based interventions have proven its efficacy in treating post-traumatic stress disorder (PTSD), but the underlying neurobiological mechanism is unknown. To determine the neurobiological mechanism of action of mindfulness-based stress reduction (MBSR) treating PTSD, we conducted a randomized clinical trial (RCT) in which 98 veterans with PTSD were randomly assigned to receive MBSR...