CNS Spectrums
August 1, 2021
Mu-Hong Chen, Wei-Chen Lin, Hui-Ju Wu et al.
AbstractBackgroundThe antidepressant effect of low-dose ketamine infusion on Taiwanese patients with anxious vs nonanxious treatment-resistant depression (ANX-TRD vs NANX-TRD) has remained unknown.MethodsIn total, 71 patients with TRD were randomized to three groups. Each group had participants who received saline infusions mixed with 0 (a normal saline infusion), 0.2, and 0.5 mg/kg of...
Oxford University Press eBooks
August 1, 2021
Chris Letheby
Philosophy of Psychedelics is the first scholarly monograph in English devoted to the philosophical analysis of psychedelic drugs. Its central focus is the apparent conflict between the growing use of psychedelics in psychiatry and the philosophical worldview of naturalism, which holds that the natural world is all that exists. The book reviews scientific evidence that psychedelics such as...
Philosophy of Psychedelics
August 1, 2021
Chris Letheby
1 citation
‘On the need for a natural philosophy of psychedelics’ provides a brief overview of the history of psychedelics in science and psychiatry, and a detailed review of recent evidence for their therapeutic and transformative efficacy. The chapter reviews clinical trials showing that one or two controlled psychedelic experiences can durably reduce symptoms of anxiety, depression, and addiction, and...
July 28, 2021
Jennifer Huberty, N. Bhuiyan, Taylor L Neher et al.
BACKGROUND Mobile meditation apps may offer a long-term, accessible, and effective solution for ongoing symptom management in cancer patients/survivors. However, there are currently no commercial cancer-specific meditation apps that reflect cancer specialist expertise, input from cancer patients/survivors, and features and content specific to cancer patients’/survivors’ needs. OBJECTIVE The aim...
July 26, 2021
Cindy Brooks Dollar
8 citations
Psychedelic research is said to be going through a renaissance with widespread public and political attention on psychedelics' ability to clinically resolve various medicalized issues.The prevailing cultural narrative of psychedelics almost touts it as a panacea when used in regulated, clinical settings under the supervision of a trained guide.While clinical studies are certainly informative,...
Mindfulness
July 16, 2021
Anuradha Baminiwatta, Indrajith Solangaarachchi
This study aimed to identify historical developments, active research areas, and emerging trends within scientific literature on mindfulness published so far, using bibliometric methods. We also aimed to identify prominent journals, authors, organizations, and countries in the field of mindfulness. Articles or reviews which mention mindfulness in the title, abstract, or keywords were identified...
Expert Review of Clinical Pharmacology
July 6, 2021
E. Schenberg
Dear Editors, Unblinding is an important confounding in pharmacological research potentially affecting rigor and objectivity of the scientific data underlying evidence-based medicine. Therefore, I want to commend the work by Muthukumaraswamy et al. [1] reporting on this problem in clinical trials with psychedelics (Ketamine, LSD, psilocybin and ayahuasca), which are rapidly becoming a focus of...
The International Journal of Neuropsychopharmacology
July 5, 2021
Sven Melker Hagsäter, Robert Pettersson, Christopher Pettersson et al.
29 citations
Abstract Background Though drugs binding to serotonergic 5-HT2A receptors have long been claimed to influence human anxiety, it remains unclear if this receptor subtype is best described as anxiety promoting or anxiety dampening. Whereas conditioned fear expressed as freezing in rats is modified by application of 5-HT2A–acting drugs locally into different brain regions, reports on the effect of...
Journal of the International Neuropsychological Society
July 1, 2021
Kelly A. Sagar, M. Dahlgren, Ashley M. Lambros et al.
Abstract Objective: Cannabis use has increased dramatically across the country; however, few studies have assessed the long-term impact of medical cannabis (MC) use on cognition. Studies examining recreational cannabis users generally report cognitive decrements, particularly in those with adolescent onset. As MC patients differ from recreational consumers in motives for use, product selection,...
Comprehensive Psychiatry
July 1, 2021
Josef J Bless, Kenneth Hugdahl, Bodil Kråkvik et al.
Few studies have investigated hallucinations that occur at the onset/offset of sleep (called hypnagogic/hypnopompic hallucinations; HHHs), despite the fact that their prevalence in the general population is reported to be higher than the prevalence of daytime hallucinations. We utilized data from an epidemiological study to explore the prevalence of HHHs in various modalities. We also...