Abstract Ayahuasca is a psychedelic brew used for centuries in religious rituals by indigenous cultures. Recent studies suggest its potential to reduce depression and anxiety and as an alternative for treating ethanol and tobacco use disorders. However, research on its impact on cocaine use disorder remains limited. We investigated the effects of ayahuasca on the reinstatement of...
Background: Premenstrual dysphoric disorder (PMDD) is a severe mood disorder characterised by depression, irritability, mood lability, anxiety and physical symptoms that occur exclusively in the last week/s of the menstrual cycle. With a growing global interest in microdosing of psychedelic drugs, an increase in self-medication has occurred, including by those with PMDD. Aim: Qualitative...
EMJ spoke with Christina Dalla, a pioneering researcher in neuropsychopharmacology and expert in sex differences in neuropsychiatric disorders, to discuss her most impactful discoveries in depression and anxiety, and the potential of psychedelic treatments in mental health.
arXiv Preprint ArchiveJuly 23, 2025Mohammad Nur Hossain Khan, David Creswell, Jordan Albert et al.
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Mindfulness training is widely recognized for its benefits in reducing depression, anxiety, and loneliness. With the rise of smartphone-based mindfulness apps, digital meditation has become more accessible, but sustaining long-term user engagement remains a challenge. This paper explores whether respiration biosignal feedback and mindfulness skill estimation enhance system usability and skill...
Gestational diabetes mellitus (GDM) is a prevalent metabolic disorder that can occur during pregnancy, leading to various complications for both the mother and the fetus. Additionally, women with gestational diabetes are at a higher risk of experiencing mental health disorders. This study was conducted to investigate the impact of group counselling based on mindfulness on perceived stress in...
Deficits in positive emotion regulation (PER) contribute to emotional disorders but are less studied than negative emotion regulation (NER). One maladaptive PER strategy, positive emotion contrast-seeking (PEC-seeking), involves sustaining negative affect to enhance later positive emotions, reinforcing anxiety and depression. This study developed and tested a savoring-based, transdiagnostic...
Introduction Mindfulness-Based Stress Reduction (MBSR) is increasingly recognized for its role in improving university students' mental health and academic performance. This systematic review evaluates the impact of MBSR on stress, anxiety, depression, cognitive flexibility, and emotional regulation. Methods Following PRISMA guidelines, 34 high-quality studies published between 2012 and 2024...
A revolutionary change in contemporary therapeutic paradigms may be seen in the renewed interest in psychedelic plant remedies. Psychedelic plants like psilocybe mushrooms, ayahuasca, iboga, and salvia divinorum, which have long been valued for their spiritual and therapeutic qualities in a variety of cultures, are now the subject of intense scientific research. According to recent clinical...
Comorbid mental health symptoms impact 30-40% of cancer patients, significantly compromising treatment adherence and increasing mortality rates. Among patients undergoing radiation therapy, which is delivered with palliative intent in nearly half of all cases and for those nearing end-of-life, these rates may be even higher. Emerging research underscores the promising potential of...
People with HIV (PWH) are disproportionately affected by cigarette use, with a 40 - 70% prevalence rate. Although many express a strong interest in quitting, many PWH who smoke experience lower cessation rates with traditional treatments, in part due to their comorbid anxiety and depressive symptoms. Psilocybin, a classic psychedelic referred to as "breakthrough therapy" by the U.S. Food & Drug...