Page 864 of 869: studies 8,631 to 8,640 of 8,687, newest first. Back to the addiction overview
Jae Lee preprint
This paper addresses the mind-body problem by highlighting the concept of continuity. Building on philosophical definitions, it introduces an "ontology of continuity" thesis to bridge the mental and the physical. Based on the thesis, the paper introduces a “neuro-subjective interactive (NSI)” model, which incorporates empirical studies from brain science. The model suggests that subjective...
Li Sun preprint
Abstract The increasing use of digital technologies in daily life has led to a growing number of studies in the field of digital psychology. While research in this area has provided valuable insights into the potential benefits and drawbacks of digital technologies for mental health and well-being, there is still much to be learned about the complex relationship between technology and...
Patrick Ryan preprint
Hallucination is typically considered cognitive noise—an error requiring correction in both human and artificial intelligences. This thesis, however, positions hallucination as an essential generative function of sophisticated cognitive systems, whether biological or artificial. It explores historical and philosophical foundations—from Plato's Allegory of the Cave and Descartes' radical...
Vincent Joralemon preprint
Psychedelic therapies—ketamine, MDMA, psilocybin, LSD, DMT, and ibogaine—are moving from prohibition to regulated care, but commercialization hinges on FDA approval, DEA scheduling, and payor (insurance) coverage. This Article maps the U.S. regulatory labyrinth and analyzes how business models succeed or fail under these constraints. It explains bifurcated rescheduling (DEA reschedules the...
Timo Faustmann, Stephan Theiss, Philipp Görtz et al.
Abstract Phencyclidine (PCP), a non-competitive N-methyl-D-aspartate receptor antagonist, is known to produce schizophrenia-like psychosis in humans, including positive and negative symptoms as well as cognitive dysfunction. Moreover, acute administration of PCP can emulate corresponding behavioral symptoms in rodents. We investigated the effect of PCP and the possible rescuing potential of...
Dustin Marlan preprint
The law has long protected movement through physical space. This Article asks whether it should also protect movement through mental space. Psychedelics are reemerging in law and culture after decades of prohibition, but the prevailing justifications for reform--medical utility, religious freedom, neurodiversity, free speech, and especially cognitive liberty--either protect too few or fail to...
Athokpam Langlen Chanu, Youngjai Park, Jaesung Choi et al. preprint
We analyze electroencephalography (EEG) signals using the ordinal pattern framework to investigate whether different human brain states can be distinguished based on the disorder of EEG dynamics. Rather than analyzing raw EEG signals, we focus on the principal mode of EEG phase dynamics, reflecting anterior–posterior information flow, and quantify disorder using permutation entropy. We apply...
Sonia Medina, Owen G. O’Daly, Matthew A. Howard et al. preprint
Abstract Mind-body treatments can improve coping mechanisms, and occasionally perceived pain, in individuals with Fibromyalgia syndrome (FMS). However, their mechanisms-of-action remain unclear and predictors of treatment response are lacking. We employed resting-state blood oxygen level dependent (rsBOLD) functional magnetic resonance imaging (fMRI) to address this need by examining changes in...
Szilvia Kresznerits, Ágnes Zinner-Gérecz, Mónika Miklósi et al. preprint
Abstract Background Non-suicidal self-injury (NSSI) is highly prevalent among individuals with borderline personality disorder (BPD) and is one of the most robust predictors of future suicide attempts and suicide deaths. Access to comprehensive treatments such as dialectical behaviour therapy remains limited. Methods This exploratory study evaluated the feasibility and preliminary outcomes of a...
Kathryn R. Hefner, Mark. J. Starr, John Joseph Curtin preprint
Marijuana is the most commonly used illicit drug in the United States and its use is rising. Nonetheless, scientific efforts to clarify the risk for addiction and other harm associated with marijuana use have been lacking. Maladaptive decision-making is a cardinal feature of addiction that is likely to emerge in heavy users. In particular, distorted subjective reward valuation related to...