Journal of Cognitive Neuroscience
December 1, 2012
Kyle E Mathewson, Christopher Prudhomme, Monica Fabiani et al.
Rhythmic events are common in our sensory world. Temporal regularities could be used to predict the timing of upcoming events, thus facilitating their processing. Indeed, cognitive theories have long posited the existence of internal oscillators whose timing can be entrained to ongoing periodic stimuli in the environment as a mechanism of temporal attention. Recently, recordings from primate...
December 1, 2012
D. Compton, Melissa C. Selinger, E. Westman et al.
Fo xy or Methoxy Fo xy (5-MeO-DIPT) is one of a series of new "club drugs" that within the past decade has gained in popularity among recreational users as an alternative to MDMA (Ecstasy). Unlike M DMA, not much is known about the neurobiological consequences of 5-MeO-DIPT use. Little is known about the effects of either co mpound on learning in a nonspatial appetitive task. In the present...
Journal of Addiction Research & Therapy
December 1, 2012
Lucas R. Watterson, L. Hood, Kaveish Sewalia et al.
71 citations
Methylone is a member of the designer drug class known as synthetic cathinones which have become increasingly popular drugs of abuse in recent years. Commonly referred to as “bath salts”, these amphetamine-like compounds are sold as “legal” alternatives to illicit drugs such as cocaine, methamphetamine, and 3,4-methylenedioxymethamphetamine (MDMA, ecstasy). Following their dramatic rise in...
Translational Psychiatry
November 27, 2012
Kelly A. Gleason, Shari G. Birnbaum, Abhay Anand Shukla et al.
79 citations
Clinical studies report associations between cannabis use during adolescence and later onset of schizophrenia. We examined the causal relationship between developmental cannabinoid administration and long-term behavioral and molecular alterations in mice. Mice were administered either WIN 55,212-2 (WIN), a cannabinoid receptor 1 (CB1) agonist or vehicle (Veh) during adolescence (postnatal day...
Neuroimage
November 15, 2012
Linda E. Klumpers, David M. Cole, Najmeh Khalili-Mahani et al.
Resting state-functional magnetic resonance imaging (RS-FMRI) is a neuroimaging technique that allows repeated assessments of functional connectivity in resting state. While task-related FMRI is limited to indirectly measured drug effects in areas affected by the task, resting state can show direct CNS effects across all brain networks. Hence, RS-FMRI could be an objective measure for compounds...
Biological Psychiatry
November 15, 2012
Mohini Ranganathan, Ashley Schnakenberg, Patrick D. Skosnik et al.
125 citations
Salvia divinorum (Salvia) is an increasingly popular recreational drug amongst adolescents and young adults. Its primary active ingredient, Salvinorin A (SA)-a highly selective agonist at the κ opiate receptor-is believed to be one of the most potent naturally occurring hallucinogens. However, there is little experimental data on the effects of SA in humans. In a 3-day, double-blind,...
Journal of Psychoactive Drugs
November 1, 2012
Michael Lyvers, Molly Meester
97 citations
Psychedelic drugs have long been known to be capable of inducing mystical or transcendental experiences. However, given the common "recreational" nature of much present-day psychedelic use, with typical doses tending to be lower than those commonly taken in the 1960s, the extent to which illicit use of psychedelics today is associated with mystical experiences is not known. Furthermore the mild...
Journal of Neuroscience
October 31, 2012
Micah Allen, Martin Dietz, Karina S. Blair et al.
389 citations
Mindfulness meditation is a set of attention-based, regulatory, and self-inquiry training regimes. Although the impact of mindfulness training (MT) on self-regulation is well established, the neural mechanisms supporting such plasticity are poorly understood. MT is thought to act through interoceptive salience and attentional control mechanisms, but until now conflicting evidence from...
Journal of Vision
October 25, 2012
Bernhard Schlagbauer, Hermann J Müller, Michael Zehetleitner et al.
38 citations
In visual search, context information can serve as a cue to guide attention to the target location. When observers repeatedly encounter displays with identical target-distractor arrangements, reaction times (RTs) are faster for repeated relative to nonrepeated displays, the latter containing novel configurations. This effect has been termed "contextual cueing." The present study asked whether...
Journal of Neurochemistry
October 20, 2012
Lucia Frau, Nicola Simola, Antonio Plumitallo et al.
46 citations
Abstract Evidence is accumulating to suggest that 3,4‐methylenedioxymethamphetamine ( MDMA ) has neurotoxic and neuroinflammatory properties. MDMA is composed of two enantiomers with different biological activities. In this study, we evaluated the in vivo effects of S(+)‐ MDMA , R(−)‐ MDMA , and S(+)‐ MDMA in combination with R(−)‐ MDMA on microglial and astroglial activation compared with...