Journal of Psychopharmacology
April 2016
Stephen J. Kaar, Jason Ferris, Jon Waldron et al.
In recent years the recreational use of inhaled nitrous oxide gas (N2O) is becoming increasingly popular, yet little is known about the characteristics of its users or the effects they experience. This paper presents original research from the 2014 Global Drug Survey (GDS) (n=74,864). GDS runs the largest survey of recreational drug use in the world. The findings confirm N2O as a very common...
Open Mind
April 1, 2016
Michelle Carr
2 citations
La littérature suggère que le sommeil paradoxal joue un rôle dans l'intégration associative de la mémoire émotionnelle. De plus, les rêves en sommeil paradoxal, en particulier leur nature bizarre et émotionnelle, semblent refléter cette fonction associative et émotionnelle du sommeil paradoxal. La conséquence des cauchemars fréquents sur ce processus est inconnue, bien que le réveil provoqué...
Behavioural Pharmacology
April 1, 2016
Cristiano Chiamulera, Federica Armani, Anna Mutti et al.
Methoxetamine (MXE) is a chemical analogue of ketamine. Originally proposed as a ketamine-like fast-acting antidepressant, owing to similar N-methyl-D-aspartate blocker properties, it is now scheduled for reports of hallucinations and psychosis similar to ketamine and lysergic acid. As little is known about the addictive properties of MXE, the aim of this study was to investigate the similarity...
Neurotoxicity Research
April 1, 2016
Krystyna Gołembiowska, Alexandra Jurczak, Katarzyna Kamińska et al.
New psychoactive “designer drugs” are synthetic compounds developed to provide similar effects to illicit drugs of abuse, but not subjected to legal control. The rapidly changing legal status of novel psychoactive drugs triggers the development of new compounds, analogs of well-known amphetamine or mescaline. New designer drugs used as substitutes in ecstasy pills are the least investigated and...
Cellular and Molecular Life Sciences
April 1, 2016
Jian Xu, Pradeep Kurup, Tyler D Baguley et al.
Brain-derived neurotrophic factor (BDNF) and STriatal-Enriched protein tyrosine Phosphatase 61 (STEP61) have opposing functions in the brain, with BDNF supporting and STEP61 opposing synaptic strengthening. BDNF and STEP61 also exhibit an inverse pattern of expression in a number of brain disorders, including schizophrenia (SZ). NMDAR antagonists such as phencyclidine (PCP) elicit SZ-like...
The FASEB Journal
April 1, 2016
Kelly Jean Sherman, Charles D. Nichols
Circadian rhythms modulate biochemical and molecular pathways in living systems. In humans an endogenous clock mechanism is synchronized by a daily light‐dark cycle: sun up and sun down. These external cues from the environment regulate the core‐clock through auto‐regulating circadian genes’ expression levels. These oscillating gene products modulate physiological, biochemical, and molecular...
Social & Cultural Geography
March 31, 2016
Jonathan Thomas Lowell, Paul C. Adams
16 citations
This paper examines the Santo Daime religion, the Amazonian town of Céu do Mapiá which is one of its primary spiritual centres, and Ayahuasca, a key sacrament of the Santo Daime religion. The small village in the Amazon demonstrates the active outreach by a place which functions as a nexus of international and intercontinental flows of substances, bodies and meanings. The power of place is...
Temperature
March 30, 2016
Sandra L Hrometz, Jeremy A Ebert, Karen E Grice et al.
Fatal hyperthermia as a result of 3,4-methylenedioxymethamphetamine (MDMA) use involves non-esterified free fatty acids (NEFA) and the activation of mitochondrial uncoupling proteins (UCP). NEFA gain access into skeletal muscle via specific transport proteins, including fatty acid translocase (FAT/CD36). FAT/CD36 expression is known to increase following chronic exercise. Previous studies have...
International Journal of Indian Psychology
March 25, 2016
The relationship between anxiety and impaired academic performance has been well documented by a number of investigators (Tyron, 1980; Hill & Wigfield, 1984; Topp, 1989; Sud & Sharma, 1990; Zeidner, 1990; Zoller & Ben-chain, 1990). Everyone should feel somewhat anxious before they begin to take a test. Anxiety becomes a problem when it begins to interfere with a student’s ability to think...
Therapeutic Advances in Psychopharmacology
March 23, 2016
Saibal Das, Preeti Barnwal, Anand Ramasamy et al.
51 citations
Lysergic acid diethylamide (LSD), described as a classical hallucinogen, began its journey from the middle of the last century following an accidental discovery. Since then, it was used as a popular and notorious substance of abuse in various parts of the world. Its beneficial role as an adjunct to psychotherapy was much unknown, until some 'benevolent' experiments were carried out over time to...