In this article I examine an important episode in the growth of ‘mindfulness’ as a biomedical modality in Britain: the formation and establishment of Mindfulness-Based Cognitive Therapy (MBCT) by John Teasdale and his colleagues Mark Williams and Zindel Segal. My study, focusing on Teasdale’s contribution, combines ethnographic, oral historical and archival research to understand how...
Addiction can cause many problems for the addict and family, so that the addict's family suffers from more problems.Addicts' wife suffer more psychological and marital problems.The aim of this study was to investigate the effect of mindfulness training on reducing couple burnout of addict's wife.The study was quasiexperimental that used the pretest-posttest whit control group.The population of...
Background: Quality of life (QOL) is always considered as a final consequence of clinical trials, interventions, and health care. The results of studies indicate that addiction leads to lower QOL. However, studies have been conducted on the effectiveness of mindfulness-based interventions on improving QOL. The aim of this study was to investigate the efficacy of mindfulness-based relapse...
Science AdvancesOctober 2018A Chicca, M A Schafroth, I Reynoso-Moreno et al.
Phytochemical studies on the liverwort Radula genus have previously identified the bibenzyl (-)-cis-perrottetinene (cis-PET), which structurally resembles (-)-Δ9-trans-tetrahydrocannabinol (Δ9-trans-THC) from Cannabis sativa L. Radula preparations are sold as cannabinoid-like legal high on the internet, even though pharmacological data are lacking. Herein, we describe a versatile total...
Research suggests sleep plays a role in the consolidation of recently acquired memories for long-term storage. rapid eye movement (REM) sleep has been shown to play a complex role in emotional-memory processing, and may be involved in subsequent waking-day emotional reactivity and amygdala responsivity. Interaction of the hippocampus and basolateral amygdala with the medial-prefrontal cortex is...
Biochemical PharmacologyOctober 2018John T Rodgers, Nadezhda Y Davydova, Erickson M Paragas et al.
We investigate the mechanism of time-dependent inhibition (TDI) of human cytochrome P450 2D6 (CYP2D6) by 3,4-methylenedioxymethamphetamine (MDMA, ecstasy), one of the most widespread recreational drugs of abuse. In an effort to unravel the kinetic mechanism of the formation of metabolic inhibitory complex (MIC) of CYP2D6 with MDMA-derived carbene we carried out a series of spectrophotometric...
O canto dos Shipibo-Konibo (grupo indígena das terras baixas peruanas) em curasrituais revela que um marcador de tempo em sua linguagem vernacular pode se referir aum passado mítico e a um “mundo espiritual” do presente. Neste artigo serãoapresentados e analisados o passado recente do grupo no que diz respeito à bebidaayahuasca, o significado de seus trançados e sua identidade “étnica”. Aqui...
The article deals with the question of the possibility of implementing phenomenological project, which is aimed at understanding of the whole content of experience constituted by consciousness. To achieve the goal of transcendental philosophy – a clear understanding of oneself as the subjectivity functioning as primarily source – E. Husserl moves from description of things of the intuited...
Rhythmic neuronal synchronization across large-scale networks is thought to play a key role in the regulation of conscious states. Changes in neuronal oscillation amplitude across states of consciousness have been widely reported, but little is known about possible changes in the temporal dynamics of these oscillations. The temporal structure of brain oscillations may provide novel insights...
Sub-anesthetic ketamine produces rapid antidepressant effects in patients with bipolar and unipolar major depression where conventional monoaminergic-based antidepressant drugs have been ineffective or ridden with side effects. A single ketamine infusion can produce antidepressant effects lasting up to two weeks, and multiple ketamine infusions prolong this effect. Pre-clinical studies are...